Open Rank Laboratory Science Professional – Pediatric Cardiology Research

About the role

The overall focus of this translational research program is to better understand the unique adaptations governing pathological cardiac remodeling and the progression to heart failure in pediatric patients with complex congenital heart disease, including hypoplastic left heart syndrome and other single ventricle defects. This Laboratory Science Professional will have a key role in conducting a variety of experiments exploring the molecular and functional metabolic changes related to heart failure progression in this population. We utilize human tissue and blood samples in addition to cell culture- and murine- based models to conduct experiments evaluating molecular transcriptomic, proteomic, and functional alterations associated with heart failure progression. This work will be important for the identification and development of drug therapies that improve cardiac function and enhance transplant-free survival in a population with few other options.

Responsibilities

• Cell culture
• In vivo and ex vivo murine model work
• Human blood sample processing
• Molecular and cell biology techniques (RNA, DNA, protein, enzyme activity)
• Mitochondrial metabolic function assessment (Seahorse, Oroboros O2K)
• General laboratory maintenance, including reagent preparation, ordering, organization, and inventory cataloging

Requirements

• Minimum Qualifications: Entry Level - Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field
• One (1) year professional-level research experience

Qualifications

• Master’s degree in biology, molecular biology, chemistry, genetics, or related field
• Two (2) years of experience in an experimental or wet laboratory
• Training in molecular techniques with a good theoretical understanding and experience in interpretation of results
• Experience using rodent models
• Laboratory management skills

Skills, Knowledge, and Abilities

• Proficient knowledge of basic laboratory techniques, including safety procedures and techniques
• Ability to communicate effectively, both in writing and orally
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
• Outstanding customer service skills
• Demonstrated commitment and leadership ability to advance diversity and inclusion
• Knowledge of basic human anatomy, physiology, and medical terminology
• Ability to interpret and master complex research protocol information

Why Join Us

With an abundance of sunshine and mountains nearby, the Colorado Front Range is the place to be! The University of Colorado Denver, Anschutz Medical Campus as a whole, ranks among the top 20 medical centers in the country. CU Anschutz has top-ranked clinical programs in family medicine and pediatrics, and the basic science and applied health research programs attract more NIH funding than any other university in Colorado. CU-Anschutz is home to the University of Colorado Hospital, The Children’s Hospital of Colorado, and the University of Colorado Schools of Medicine, Nursing, Dentistry, Pharmacy and Pharmaceutical Sciences, and Public Health, providing access to an array of possibilities to improve lives across a spectrum of ages and disease states. Across several labs at Children’s Hospital Colorado and the Anschutz Medical Campus, teams of researchers, including ours, are investigating the early heart from an ever-growing array of angles, to develop the critical knowledgebase and infrastructure necessary to identify efficacious therapies to improve outcomes in pediatric patients. The Pediatric Heart Tissue and Blood Bank is one of the largest pediatric biobanks in the country and serves as an incredible resource for these translational studies.

Why work for the University?

• Azimuth of benefits including medical, dental, disability, life, vision, retirement, paid time off, and tuition assistance
• Exceptional amounts of holiday, vacation, and sick leave
• CU Anschutz is home to the University of Colorado Hospital, The Children’s Hospital of Colorado, and the University of Colorado Schools of Medicine, Nursing, Dentistry, Pharmacy and Pharmaceutical Sciences, and Public Health, providing access to an array of possibilities to improve lives across a spectrum of ages and disease states

How to Apply

For full consideration, please submit the following document(s): A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position, Curriculum vitae / Resume, Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address. Applications are accepted electronically ONLY at www.cu.edu/cu-careers. Questions should be directed to: Anastacia (Tasha) Garcia, PhD (Anastacia.Garcia@CUAnschutz.edu).

Equal Employment Opportunity Statement

The University of Colorado is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

ADA Statement

The University of Colorado will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Vaccination Statement

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.