Molecular & Cell Biology Senior Research Scientist
About the role
Vertex is seeking a highly motivated Senior Research Scientist, Molecular & Cell Biology to join the Human Cell Models group in Boston Research. In this role, you will develop, characterize, and apply physiologically relevant human cellular models using stem cells and primary cells to deepen understanding of disease biology, identify therapeutic opportunities, and support the advancement of novel drug discovery programs. The successful candidate will bring deep expertise in disease modeling, with particular strength in neuronal model development using induced pluripotent stem cells (iPSC) and/or primary cells. This individual will have demonstrated experience developing neuronal models (i.e. dopaminergic neurons, cortical neurons, neuronal progenitors) using iPSCs including initial optimization and characterization through robust execution and application. The successful candidate will collaborate closely with multidisciplinary partners in early research, screening, pharmacology, chemistry, and computational genomics groups to generate high-quality data and translate scientific findings into actionable program decisions. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Responsibilities
- Design, execute, analyze, and communicate rigorous cellular and molecular biology studies supporting predictive disease modeling and drug discovery