Medical Director, US Medical Affairs

Role Summary

The US Medical Director of Medical Affairs leads Dyne’s medical strategy and execution within the United States, focusing on launch readiness, US-specific KOL engagement, congress planning and execution, and supports real-world evidence (RWE) initiatives. This role ensures alignment with global strategy while tailoring activities to US regulatory, payer, and healthcare landscapes. This role leads efforts to communicate and disseminate scientific and clinical information, engage with medical professionals in the field and contribute to the overall success of the company’s portfolio.

Primary Responsibilities

• Develop and execute US Medical Affairs strategy aligned with global objectives and US market needs
• Act as point person for all US Medical Affairs launch readiness activities, including working closely with global medical director and scientific communications on development of scientific platform development, local congress planning, and local medical education programs
• Support congress strategy execution in the US, including booth activities, symposia, and scientific presentations
• Work closely and with the Head of the Medical Science Liaison (MSL) team on US KOL engagement strategy: identify, map, and build relationships with key US experts
• Develop US Medical Affairs advisory board strategy and organize and execute advisory boards and expert panels
• Collaborate with HCP and Patient Marketing as well as cross-functional stakeholders to integrate medical perspectives into brand strategy, ensuring alignment with scientific and commercial objectives
• Partner with Clinical Development and Clinical Operations to support US trial site engagement and recruitment strategies
• Identify opportunities to generate real-world evidence (RWE) and phase IV data to address data gaps and support HCP and payer treatment decisions
• Ensure compliance with US regulatory and legal requirements for all medical activities
• Serve as subject matter expert on neuromuscular diseases and Dyne’s therapeutic platforms for US stakeholders
• Support the review and approval of externally presented materials through the Medical Review committee and Promotional Review Committee
• Act as a role model for integrity and compliance in all interactions

Education And Skills Requirements

• Doctorate degree (MD, PhD, PharmD) with experience in rare diseases; neuromuscular experience preferred
• Minimum 8 years of relevant experience in Medical Affairs within the US pharmaceutical/biotech industry
• Proven ability to lead US launch readiness and medical strategy execution
• Excellent communication and relationship-building skills with US KOLs and cross-functional teams
• Ability to interpret and communicate complex scientific data to diverse audiences
• Effective communication skills (written, verbal and presentation)
• Willingness to travel up to 30%, inclusive of overnight and occasional weekends to meet with customers, internal stakeholders and attend relevant conferences
• Candidates must be authorized to work in the U.S.

Positive Team Member Who Embodies Dyne’s Core Values

Excitement about Dyne’s vision and mission

Experience Managing Direct Reports

Not specified

MA Pay Range

$196,000—$285,000 USD