Medical Director, Clinical Development

About the Role

We are seeking a driven and strategic Medical Director, Clinical Development to lead clinical development efforts across one or more early- or late-stage programs. This pivotal role offers the opportunity to shape clinical strategy, serve as medical monitor, and collaborate cross-functionally to drive execution. Depending on business needs, the role may also include mentoring clinical scientists and contributing to business development and process improvement initiatives.

Responsibilities

• Clinical Development Leadership (75%):
  • Lead clinical strategy and execution for one or more programs; serve as medical monitor and oversee study-level activities.
  • Conduct data review in collaboration with clinical science and safety; author clinical and regulatory documents (e.g., protocols, IBs, INDs).
  • Engage with KOLs, lead advisory boards and steering committees, and support publications.
  • Present findings to leadership and contribute to the scientific and commercial advancement of pipeline assets.
• Organizational Contribution & Cross-Functional Collaboration (25%):
  • Partner cross-functionally to drive alignment, communication, and operational excellence across teams as well as between Ono and Deciphera.
  • Contribute clinical insights to target assessments, business development, and strategic initiatives.
  • Support Medical Affairs and serve as a clinical liaison for study sites and internal teams.
  • Participate in continuous improvement efforts and help foster a collaborative company culture.

Requirements

• MD (or equivalent) with 8+ years of academic/industry experience, including 3+ years in clinical trials.
• Proven experience in trial design, execution, and medical monitoring.
• Strong understanding of GCP/ICH and global regulatory standards.
• Familiarity with data review tools (e.g., Rave, J-Review, Spotfire).
• Excellent leadership, communication, and cross-functional collaboration skills.
• Ability to work across time zones and up to 30% travel.

Preferred Qualifications

• Board-certified in Medical Oncology.
• Experience across Phases 1–3 of clinical development.
• Direct interaction with U.S. and ex-U.S. regulatory agencies.
• Background in basic or translational research.

Pay

The base salary pay range for this role is $243,300 - $334,590. Actual compensation packages will depend on various factors, including depth of experience, education, skillset, overall performance, and/or location.

Benefits

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.