MEDICAL DIRECTOR

Responsibilities

• Provide medical leadership for the design, execution, and interpretation of Phase 1/2 oncology clinical trials, with a focus on ADC programs
• Serve as medical monitor for assigned studies, ensuring patient safety, protocol compliance, and high-quality data
• Lead development of clinical protocols, investigator brochures, clinical study reports, and other key regulatory documents
• Contribute to and help shape overall clinical development strategy for ADC assets, including first-in-human studies and expansion cohorts
• Partner closely with translational sciences to integrate biomarker strategies, PK/PD insights, and mechanism-of-action data into clinical development plans
• Collaborate cross-functionally with clinical operations, regulatory affairs, CMC, nonclinical, and biometrics teams to ensure seamless program execution
• Engage and build strong relationships with key opinion leaders, investigators, and academic collaborators in oncology
• Support regulatory strategy and interactions, including preparation for FDA and global health authority meetings
• Analyze and interpret emerging clinical and translational data to inform dose selection, safety management, and program decisions
• Contribute to scientific publications, conference presentations, and external communications

Qualifications

• MD or MD/PhD required; board certification or eligibility in Oncology or Hematology/Oncology preferred
• Minimum of 2-5+ years of relevant experience with a minimum of 2 years of oncology clinical trial experience in pharmaceutical or biotech industries preferred
• Demonstrated experience leading or contributing to early-phase (Phase 1 and/or Phase 2) oncology clinical trials
• Prior experience with antibody-drug conjugates (ADCs) strongly preferred; experience with targeted therapies or biologics is a plus
• Solid understanding of oncology drug development, including clinical endpoints, dose escalation strategies, safety monitoring, and regulatory requirements
• Experience serving as a medical monitor on a registration study and interacting with regulatory agencies (e.g., FDA)
• Knowledgeable and current in GCP guidelines in US and Europe
• Strong scientific, analytical, and strategic thinking skills, with the ability to interpret complex clinical and translational data
• Proven ability to work effectively in a cross-functional, fast-paced biotech environment
• Up to 25% travel (US and international)

Preferred Attributes

• Experience with novel payloads, linker technologies, or platform-based drug development approaches
• Familiarity with resistance mechanisms and combination strategies in oncology
• Background in translational medicine and biomarker-driven development
• Track record of scientific publications and external presentations
• Demonstrated commitment to high personal values and ethical standards

Benefits

The anticipated salary range for fully qualified candidates applying for this role at Sutro Biopharma’s California based locations will be $245,000 - $300,000 (not including bonus, equity, and benefits).

Pay

The final salary offered will be dependent on several factors that include and are not limited to relevant previous experience, job responsibilities and duration of experience, the type and length of experience within the industry and education.

Schedule

Not specified