Managing Director, BCRF Venture Philanthropy Program
The Breast Cancer Research Foundation · New York, NY · 1 mo ago
HybridSales$45k–$475k/yrFull-time
We need to output HTML fragment with sections: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule as needed. The posting includes sections: About Bcrf (intro), About The Role, Primary Responsibilities, About You, In Addition, You Have The Following Qualifications And Experience, Strongly Preferred Experience.
We need to map to headings: About the role (maybe combine About The Role and About You?), Responsibilities (Primary Responsibilities), Requirements (maybe combine qualifications?), Qualifications (maybe the list of qualifications), Skills (maybe skills from qualifications), Benefits, Pay, Schedule (none given). We must only include sections when posting has real specific content. No Pay or Schedule mentioned, so omit those sections. Benefits? Not mentioned. So we can omit Benefits, Pay, Schedule.
We need to include About the role heading (
About the role
) with content from About The Role paragraph(s). Should we include the introductory BCRF description? That is about the organization, not the role. The instruction: "Do NOT repeat the job title as a heading (the page already shows it)". The job title is Managing Director. The "About The Role" section is appropriate. We need to include Responsibilities heading with Primary Responsibilities content (bulleted list). Use- . Qualifications heading: include the qualifications list (minimum 10 years etc). Also maybe include "In Addition, You Have The Following Qualifications And Experience". That's qualifications. Skills heading: maybe include skills like communication, relationship building, etc. Could extract from qualifications: "Excellent written and verbal communication skills...", "Proven ability to build and maintain trusted relationships...". We'll put those under Skills. We must preserve all substantive information, not invent or summarize away detail. Must not omit details. So we need to include all content from the posting under appropriate sections. We must remove boilerplate like cookie/navigation/legal/EEO etc. Not present. We must not include duplicated lines. We need to output only HTML fragment, no /, no markdown fences. Let's extract content. First, About The Role section text: "BCRF is seeking a founding Managing Director (MD) — an exceptional individual who will build and lead the Venture Philanthropy Program from the ground up. This is a rare opportunity to shape a mission-driven investment program that will directly influence the pace of breast cancer drug, diagnostic, and prevention technology development globally, backed by the credibility and scientific network of the world's largest private funder of breast cancer research. At $100 million, the Program is sized not merely to catalyze individual discoveries, but to reshape the early-stage breast cancer investment ecosystem. The Program will build a diversified portfolio of 20 to 30 companies over five to seven years, with BCRF moving from participant to lead investor: structuring deals, convening co-investment syndicates, and negotiating mission-protection covenants alongside leading oncology venture capital firms. "The Program will exhibit the discipline of venture capital, and the patience and purpose of philanthropy. The Managing Director will be the embodiment of both." The MD will serve as the Program's chief investment officer and primary operational executive, responsible for the full investment lifecycle — strategy, sourcing, scientific and business evaluation, deal structuring, Investment Committee management, portfolio oversight, and performance reporting — and will build the Program's founding team, including an Investment Principal, Operations Manager, and Associate over the course of Year 1. The MD will also serve as the Program's primary external representative to the venture capital and biopharmaceutical communities, and as a senior ambassador for BCRF's mission to donors, scientific collaborators, and the broader breast cancer community. The ideal candidate will bring a distinctive combination of deep scientific and clinical knowledge of oncology — ideally breast cancer — and demonstrated investment experience in early-stage biotechnology. This dual expertise is the defining requirement of the role: the Program must evaluate the scientific and clinical merit of investment opportunities as its primary objective, while maintaining the financial discipline expected for a nonprofit mission program. BCRF’s offices are in New York. While candidates based in the New York Metro area are preferred, BCRF is open to locating the Venture Philanthropy Program in the Boston, Massachusetts area and will consider exceptional candidates from the greater Boston area for this position. BCRF currently requires staff to work onsite a minimum of three days per week, and this requirement will apply to the Venture Philanthropy team." We need to keep that as prose under About the role. Now Responsibilities: Primary Responsibilities section includes several bullet-like paragraphs. Let's extract each responsibility bullet. The text: "Primary Responsibilities Reporting to the BCRF President & Chief Executive Officer and working in close partnership with the Program's Investment Committee, the Managing Director will be accountable for the full operating lifecycle of the BCRF Venture Philanthropy Program. Investment Strategy and Execution Develop, refine, and implement the Program's investment strategy, ensuring consistency with BCRF's mission and the Investment Thesis.Lead all aspects of deal sourcing, scientific and business due diligence, term sheet negotiation, investment structuring, and closing across all three investment tiers.Build and maintain a high-quality pipeline of 100–120 annual investment opportunities, managing the funnel from initial intake through Investment Committee review and approval.Prepare comprehensive investment memoranda and present investment recommendations to the Investment Committee.Assume Board observer roles at portfolio companies on behalf of BCRF Ventures, LLC.Evaluate and recommend follow-on investments in portfolio companies based on milestone achievement and evolving strategic rationale. Scientific and Clinical Leadership Serve as the Program's primary scientific and clinical intelligence resource, maintaining current, expert-level knowledge of the breast cancer research landscape across subtypes (TNBC, HER2+, HER2-low, HR+, inflammatory, metastatic).Evaluate the scientific and clinical merit of investment candidates, including mechanism of action, preclinical and clinical data packages, biomarker strategies, regulatory pathway feasibility, and competitive differentiation.Engage and manage external scientific and clinical Key Opinion Leaders who provide independent expert review during due diligence.Maintain active relationships with BCRF's 265+ investigator network and leverage scientific intelligence from that network to identify emerging translational opportunities. Portfolio Management Actively monitor portfolio company progress against milestones defined in investment documentation; prepare quarterly portfolio status reports for the Investment Committee.Provide strategic advisory support to portfolio companies on clinical development strategy, regulatory planning, partnership development, and financing.Identify and escalate material risks in portfolio companies — scientific, clinical, regulatory, competitive, or managerial — and recommend remediation strategies.Manage the Program's follow-on investment reserve and advise the Investment Committee on redeployment priorities. Investment Committee and Governance Coordinate all aspects of Investment Committee meeting preparation: agendas, investment packages, portfolio reports, and follow-on analyses; serve as IC Secretary.Ensure the Program operates in full compliance with BCRF's governance policies, conflict-of-interest procedures, PRI legal requirements, and BCRF's broader Code of Ethics.Support PRI qualification analysis for each investment structure.Prepare the annual Program report to the full BCRF Board of Directors. External Representation and Ecosystem Development Represent BCRF and the Program at key industry and scientific conferences, including ASCO, AACR, SABCS, the JP Morgan Healthcare Conference, and BIO.Build and maintain active relationships with life science venture capital firms, corporate VC programs, biotechnology business development leaders, academic technology transfer offices, and SBIR/STTR program officers to sustain high-quality deal flow.Partner with BCRF's development team to integrate the Program's impact narrative into BCRF's donor communications and fundraising strategy, and represent the Program to major philanthropic supporters. Develop progress reports for the Board of Directors and key donors. Team Building and Culture Recruit, mentor, and develop Program staff as the portfolio grows — including the founding Investment Principal, Operations Manager, and Associate.Build a culture of scientific excellence, investment rigor, and mission commitment within the Program team." We need to turn each bullet into
- . The headings within responsibilities (Investment Strategy and Execution, Scientific and Clinical Leadership, Portfolio Management, Investment Committee and Governance, External Representation and Ecosystem Development, Team Building and Culture) could be considered subheadings but we only need
- for list. We could either keep them as part of li text or separate headings? The instruction: Use
- for any list of duties/requirements/benefits. So we can make a list where each major duty is an li. Could include the subheading as part of li text.
Thus produce
- ... etc. Now Qualifications: The section "About You" and "In Addition, You Have The Following Qualifications And Experience". Let's extract. About You paragraph: "The Managing Director will be a highly distinguished professional whose career reflects excellence at the intersection of oncology science, clinical development, and early-stage biotechnology investment. While BCRF's Program is fundamentally a scientific enterprise focused on delivering new diagnostics and therapies to breast cancer patients, it must be administered with the financial discipline expected in a nonprofit organization. The successful candidate will most likely have built their career across two or more of the following domains: life science venture capital or corporate venture capital; pharmaceutical or biotechnology drug development; oncology clinical or translational research; or biotech business development and licensing. Candidates with a single domain of deep expertise — whether investment or science — who have not developed meaningful fluency in the other will not be considered." Then "In Addition, You Have The Following Qualifications And Experience" list: - Minimum 10 years of combined experience in life science investment and/or oncology drug or diagnostic development, with at least 5 years in a senior investment role (Principal, Partner, Managing Director, or equivalent) at a life science venture capital, corporate venture capital, growth equity, or cross-over fund. - An advanced degree is required, ideally an MD, PhD and/or MBA. - Demonstrated track record of sourcing, evaluating, structuring, and closing equity investments in early-stage oncology or broader biopharmaceutical companies. - Deep scientific and clinical knowledge of oncology, with a strong preference for direct experience in breast cancer therapeutics, breast cancer diagnostics, or an adjacent solid tumor or women's health indication. - Expert-level understanding of drug and diagnostic development processes: target identification and validation, IND-enabling studies, Phase I/II clinical trial design, biomarker strategy, FDA regulatory pathways (including Breakthrough Therapy, Fast Track, Accelerated Approval), and commercialization planning. - Experience evaluating and conducting due diligence on oncology drug candidates, including critical assessment of preclinical data packages, clinical trial data, competitive landscape analysis, and IP position. - Familiarity with investment structures used in early-stage biotech: preferred equity, convertible notes, royalty-backed financing, milestone-linked instruments, and co-investment syndication. - Proven ability to build and maintain trusted relationships with biotechnology founders and management teams, venture capitalists, pharmaceutical business development executives, and academic scientists. - Excellent written and verbal communication skills, including the ability to convey complex scientific and investment concepts to non-specialist audiences including board members, major donors, patient advocates and the media. Then "Strongly Preferred Experience" bullet: "Strongly Preferred Experience Direct experience with breast cancer biology and/or clinical oncology — including knowledge of breast cancer molecular subtypes (HR+/HER2-, HER2+, TNBC, HER2-low), current standards of care, approved and pipeline therapies, and unmet clinical needs across the disease s" It seems cut off at "disease s". Probably "disease subtypes". We'll keep as is. We need to decide headings: About the role, Responsibilities, Qualifications, Skills. Possibly also "About You" could be part of Qualifications? But we already have Qualifications heading for the list. The "About You" paragraph is more about career background; could be part of Qualifications or maybe a separate section like "Background". But we only have allowed headings: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. We can use Requirements for the "About You" career domains? Or we could put that under Qualifications as well. However we need to avoid thin sections. Let's combine: Qualifications heading includes both the "About You" career domains and the detailed qualifications list. Skills heading includes communication, relationship building, etc. But the
- for any list of duties/requirements/benefits. So we can make a list where each major duty is an li. Could include the subheading as part of li text.
Thus produce
- for list. We could either keep them as part of li text or separate headings? The instruction: Use