Jobs · Marketing · Pennsylvania

Manager, Product Technical Knowledge Specialist (MSAT)

Madrigal Pharmaceuticals · Conshohocken, PA · 2 wk ago
Marketing$140k–$172k/yrFull-time

Position Summary

The Manager, Product Technical Knowledge Specialist (MSAT) serves as a technical subject matter expert for assigned small molecule pharmaceutical products, supporting the full product lifecycle from technology transfer through commercial manufacturing and post-approval changes.

Key Responsibilities

  • Develop and maintain comprehensive technical knowledge of assigned products, including formulation, process design, critical process parameters (CPPs), critical quality attributes (CQAs), and control strategies.

  • Develops and maintains the product’s technical dossier—including process, analytical methods, controls, and key risks—serving as the single source of truth for MSAT execution.

  • Supports interpretation and application of product knowledge to manufacturing operations and process improvements.

  • Supports technology transfer to external CMOs by authoring, reviewing, and maintaining comprehensive technical transfer and process documentation, ensuring accurate and consistent knowledge transfer from development teams or prior manufacturers.

  • Supports product lifecycle activities, including post-approval changes, process optimization, continuous improvement, and deviation investigations.

  • Collaborates with Manufacturing, Process Engineering, Quality, Supply Chain, and Regulatory CMC to ensure consistent product understanding.

  • Supports inspection readiness by ensuring technical product knowledge is documented and traceable.

Required Qualifications

  • Bachelor’s degree in Chemical Engineering, Pharmaceutical Sciences, Chemistry, Biochemistry, or a related scientific discipline.

  • Minimum of 8 years experience, 3–5 years of experience in MSAT, process engineering, manufacturing support, or pharmaceutical technical operations.

  • Familiarity with GMP manufacturing environments.

  • Demonstrated understanding of pharmaceutical manufacturing processes and lifecycle support.

Preferred Qualifications

  • Experience supporting technology transfer activities.

  • Familiarity with biologics or small-molecule manufacturing (as applicable).

  • Experience contributing to deviation investigations, change controls, or process improvements.

  • Strong technical documentation and knowledge management skills.

Similar jobs