LC-MS/MS Toxicology Laboratory Supervisor

About the role

Rocky Mountain Laboratories is a clinical laboratory providing comprehensive laboratory services. We are dedicated to delivering accurate and timely diagnostic information and are committed to improving healthcare outcomes through cutting-edge technology and a customer-focused approach.

Position

Rocky Mountain Laboratories is seeking an experienced Clinical Toxicology Laboratory Supervisor with hands-on Agilent LC-MS/MS expertise and method development experience to lead our toxicology department in Draper, Utah, part of the Salt Lake City metro area.

Responsibilities

• Supervise daily toxicology laboratory operations to ensure accurate, timely, and compliant high-complexity testing
• Operate, calibrate, maintain, troubleshoot, and optimize Agilent 6460 triple quadrupole LC-MS/MS instrumentation and related platforms
• Develop, validate, and implement new analytical methods for clinical toxicology panels including drugs of abuse (DOA), pain management, and therapeutic drug monitoring (TDM)
• Lead method verification, troubleshooting, and continuous optimization of existing assays
• Oversee sample preparation workflows for urine and oral fluid specimens
• Develop, implement, and maintain Standard Operating Procedures (SOPs) for validations, clinical testing, and regulatory compliance
• Review, interpret, and authorize release of patient test results using Agilent MassHunter and other laboratory software in accordance with laboratory policies and CLIA standards
• Manage quality control (QC) and quality assurance (QA) programs; investigate out-of-range results and deviations; implement and document corrective actions
• Maintain workflow, prioritize testing queues, and allocate staff resources to meet turnaround time expectations
• Train, mentor, and evaluate laboratory staff; develop and administer competency assessments and provide ongoing technical guidance
• Serve as CLIA General Supervisor for the toxicology department, ensuring full compliance with high-complexity testing standards, OSHA safety requirements, and other applicable regulations
• Support internal inspections, CAP accreditation activities, audits, and regulatory readiness
• Collaborate cross-functionally with Chemistry, Molecular, Client Services, and other departments to resolve operational and testing issues
• Drive continuous improvement initiatives related to workflow efficiency, quality outcomes, and cost reduction
• Ensure proper handling, storage, and disposal of hazardous and biological materials
• Serve as acting department leader in the absence of the Lab Manager
• Perform other duties as assigned

Required Qualifications

• Bachelor of Science or higher in chemistry, biology, clinical laboratory science, medical laboratory science, or a closely related field
• Minimum 3 years of documented hands-on clinical toxicology experience in a CLIA-certified high-complexity laboratory, including drugs of abuse (DOA), pain management panels, or therapeutic drug monitoring (TDM), and including direct involvement in method development or validation
• Demonstrated experience independently performing the complete LC-MS/MS testing workflow — from sample preparation through instrument maintenance, method validation, data review, and result release — rather than a single specialized segment
• Recent hands-on experience operating, maintaining, and troubleshooting Agilent 6460 triple quadrupole LC-MS/MS or equivalent Agilent 6400-series instrumentation, including proficiency with Agilent MassHunter for data acquisition, analysis, and reporting
• Documented experience in LC-MS/MS method development and validation in a clinical or regulated laboratory setting
• Proficiency with sample preparation techniques, including dilute-and-shoot, solid-phase extraction (SPE), and liquid-liquid extraction (LLE)
• Strong knowledge of quality assurance, quality control principles, and corrective action processes
• Demonstrated knowledge of CLIA high-complexity testing regulations, OSHA safety requirements, and regulatory compliance
• Excellent organizational, analytical, and problem-solving skills
• Strong written and verbal communication skills
• Able to manage multiple priorities while maintaining accuracy and compliance
• 3–5+ years of clinical toxicology laboratory experience, including at least 1 year in a supervisory, lead, or certifying scientist capacity
• Experience developing or delivering competency assessments for laboratory staff
• Experience with Beckman Coulter AU 480/680 or equivalent Beckman Coulter AU-series chemistry analyzers (e.g., AU400, AU5800)
• Experience with additional LC-MS/MS platforms (e.g., SCIEX, Shimadzu, Thermo Fisher)
• Experience supporting CAP accreditation, laboratory audits, and regulatory inspections
• Familiarity with Laboratory Information Systems (LIS) and electronic reporting workflows
• Experience with high-throughput batch processing workflows in a clinical toxicology environment
• ASCP MLS(ASCP), AMT MT, NRCC, or other relevant certification
• Master's degree in chemistry, toxicology, clinical laboratory science, or a related field

Benefits for full-time W2 Team Members

• Health, Dental, and Vision Insurance
• Paid Time Off (21 days annually for full-time team members)
• 7 Paid Holidays
• 401(k) with 50% Company Match up to 6%
• Health Savings Account (HSA)
• Short-Term & Long-Term Disability (RML covers 60% of STD premium)
• Voluntary Life and AD&D Insurance
• 100% Company-Funded Employee Assistance Program (EAP)