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Jobs · Analyst · California

Large Molecule Scientific Lead

Cogent Scientific · South San Francisco, CA · 2 wk ago
On-siteAnalystFull-time

Job duties

  • Designing and executing antibody-drug conjugates (ADC) linker Structure-Activity Relationship (SAR) studies to optimize stability, hydrophobicity/hydrophilicity balance, payload release, and circulation stability.
  • Developing innovative linker designs and strategies to address limitations in existing ADC platforms.
  • Evaluating linker compatibility with diverse payload classes, including small molecules, peptides, oligonucleotides and Proteolysis-Targeting Chimeras (PROTACs).
  • Exploring linker applications in conjugates beyond antibodies to include novel delivery molecules.
  • Collaborating with internal and external teams in chemistry, biology, and analytics to advance conjugation strategies.
  • Contributing to troubleshooting and problem-solving in conjugation workflows and project execution.

Job requirements

  • BS-Chemistry, Biochemisry or a related field with 10+ years of drug development process experience, specifically with antibody-drug conjugates (ADC) and other bioconjugation modalities.
  • MS/PhD with 3+ years of above referenced experience preferred.
  • Excellent communication skills – verbal and written.
  • Works well both as a team and as an individual.
  • Demonstration of excellent team player skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.

Core Values

  • Client Focused: We only succeed when our clients succeed.
  • Outstanding: We deliver meticulous results through outstanding performance.
  • Good: We act ethically and morally.
  • Employee-Centric: We honor and support our employees.
  • Nimble: We are prepared to adapt in an ever-changing industry.
  • Team-Oriented: We collaborate with each other and with our clients.

Pay

Competitive pay.

Schedule

Day shift (approx. 8a-5p local time).

Benefits

  • Medical/dental/vision insurance
  • 401(k)
  • Parenthood leave
  • PTO and paid holidays

Company Information

We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation. Cogent Scientific offers an exciting work environment and aims to recruit the best people who stand out among their peers and embody our Core Values.

About the role

This position may include relocation benefits as well.

Qualifications

BS-Chemistry, Biochemisry or a related field with 10+ years of drug development process experience, specifically with antibody-drug conjugates (ADC) and other bioconjugation modalities. MS/PhD with 3+ years of above referenced experience preferred.

Skills

Excellent communication skills – verbal and written. Works well both as a team and as an individual. Demonstration of excellent team player skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.

Benefits

  • Medical/dental/vision insurance
  • 401(k)
  • Parenthood leave
  • PTO and paid holidays

Equal Employment Opportunity

Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.

Application Process

The job posting will remain open until 8/10/2026 or until a qualified candidate has been selected, whichever comes first.

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