Laboratory Manager - Hematology & Oncology

Responsibilities

• Perform tissue dissections and DNA and RNA extraction from mouse and human specimens.
• Support ongoing laboratory research projects and independently oversee designated scientific projects as assigned.
• Analyze experimental data and maintain accurate laboratory records.
• Collaborate with laboratory investigators and research staff on experimental design and implementation.
• Perform animal husbandry activities in compliance with Institutional Animal Care and Use Committee (IACUC) policies and federal regulations.
• Maintain mouse colonies, including genotyping, breeding and colony management.
• Organize, maintain, and update laboratory protocols, standard operating procedures (SOPs), and regulatory documentation.
• Maintain laboratory organization, cleanliness, and compliance with institutional safety, biosafety, and regulatory requirements.
• Maintain laboratory equipment and coordinate preventative maintenance, repairs, and calibration.
• Manage laboratory inventory, including ordering, receiving, and stocking reagents, consumables, and laboratory supplies.
• Maintain accurate inventory records and establish effective relationships with vendors and suppliers.
• Train and onboard laboratory personnel, students, and research staff on laboratory procedures, equipment, and safety practices.
• Coordinate laboratory purchasing, procurement activities, invoice reconciliation, and budget tracking.
• Maintain purchasing records and assist with laboratory financial management.
• Coordinate interactions with Columbia University administrative offices, core facilities, academic collaborators, and industry partners.

Qualifications

• Bachelor's degree or equivalent in education and experience, plus four years of related laboratory experience.
• A Master's degree may substitute in part for experience.
• Experience managing or organizing a mouse colony.
• Familiarity with basic molecular biology techniques.
• Strong organizational skills with exceptional attention to detail and accuracy.
• Excellent interpersonal, written, and verbal communication skills.
• Demonstrated ability to work independently while contributing effectively within a collaborative team environment.

Preferred Qualifications

• Experience with laboratory automation platforms, including the Biomek i7 or similar liquid handling systems.
• Experience with chromatin biology, epigenetics, genomics, or hematologic malignancy research.
• Experience with DNA/RNA extraction, gene expression analysis, and next-generation sequencing workflows.
• Experience assisting with grant preparation and laboratory administration.
• Prior experience managing laboratory operations in an academic research environment.