JT389 - ASSOCIATE PILOT PLANT

Responsibilities

• Supports the execution of cell culture process to include, not limited to; aseptic vial thaw & cell culture flask passaging in biosafety cabinet through benchtop wave bioreactors & 200L & 500L single use bioreactors.
• May support large scale harvest operations through downstream purification to include, but not limited to; chromatography, filtration, as well as, Ultra-Filtration/Diafiltration (UF/DF) using various Pilot Scale skids & equipment.
• May perform additional routine tasks to include, but not limited to; in-process sampling, operation of laboratory analyzers, management of samples, scientific data collection via electronic laboratory notebook(s), compounding media/buffer solutions, Clean-In-Place (CIP), Steam-In-Place (SIP), equipment assembly & disassembly, routine maintenance of benchtop analyzers, escort & provide oversight of vendors, inventory stocking as well as, general lab organization & cleaning.
• Utilizes scientific principles in execution of experiments & analysis of experimental data.
• Carries out laboratory tasks per plan & procedure in a team environment.
• Documents data & process information in accordance with good documentation practices.
• Performs laboratory safety evaluations.
• Performs minor equipment maintenance.
• Helps maintain laboratory standards with a focus on safety, quality, and compliance.

Qualifications

• Bachelor’s degree in a related science or engineering field (e.g., biology, chemistry, biopharmaceutical sciences).
• Technical Skills: Experience in cell culture (mammalian or microbial) is crucial, including aseptic handling and familiarity with bioreactors.
• Some exposure to chromatography, filtration (UF/DF), and data analysis.
• Basic knowledge of process automation systems and scientific documentation, including notebooks and batch records.
• Prior hands-on experience in pilot- or large-scale cell culture or downstream purification process development or manufacturing.
• Experience with automated computer-controlled biopharmaceutical equipment.
• Knowledge of process data compilation and analysis.
• Demonstrated problem-solving capabilities and excellent attention to detail.
• Excellent written and verbal communication skills.