Integrated Wet Lab and Computational Researcher I,, Surgery

Job Summary

Perform professional work in support of scientific research using technical knowledge of software, software development, networking, and/or hardware in a complex computing environment. Subject matter expert in multiple areas of computing technology, and specific knowledge of molecular biology and genetics. Works collaboratively with Principal Investigator ("PI") to determine the most suitable computational methods and tools to analyze large-scale biological data sets. Prepare reports for presentation or publication. Responsible for assisting PI in meeting the system needs for multiple research projects and/or labs.

Responsibilities / Essential Functions

• Analyze transcriptomic, single-cell, spatial, metabolomics, proteomics, imaging, and other high-dimensional biological datasets.
• Build reproducible Python and R workflows for preprocessing, statistical analysis, visualization, interpretation, and reporting.
• Develop predictive, machine learning/AI, and computer vision approaches for wound healing, trauma response, and tissue analysis.
• Manage laboratory computing infrastructure, including hardware, software, high-performance computing, cloud/server workflows, databases, data management, and network troubleshooting.
• Support wet-lab workflows, including animal handling, small animal procedures, histology, immunofluorescence imaging, CyTOF, flow cytometry, and mammalian cell culture.
• Document methods, prepare reports and presentations, contribute to publications, train lab staff on research systems, and collaborate with the PI, lab members, and external collaborators.
• Recommend and test new systems as needed; perform other duties as assigned.

Qualifications

• Strong R and Python skills, experience with transcriptomic analysis, statistics, visualization, data management, and biological interpretation.
• Knowledge of molecular biology, genetics, or a related biological science.
• Experience with single-cell RNA-seq, bulk RNA-seq, spatial transcriptomics, metabolomics, proteomics, machine learning/AI, computer vision, cloud computing, and workflow management.
• Wet-lab experience in animal models, histology, cell biology, or molecular cell biology.

Benefits

UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

• PPO medical plan, available day one at no cost for full-time employee-only coverage
• 100% coverage for preventive healthcare-no copay
• Paid Time Off, available day one
• Retail Savings Plan
• Retirement Programs through the Teacher Retirement System of Texas (TRS)
• Paid Parental Leave Benefit
• Wellness programs
• Tuition Reimbursement
• Public Service Loan Forgiveness (PSLF) Qualified Employer