In-House Clinical Research Associate (CRA)

About the role

We are seeking an In-House Clinical Research Associate (CRA) who’s excited to help execute fast, high-quality clinical trials that drive our mission forward. You’ll be a key player in ensuring our studies are inspection-ready, patient-centric, and run with rigor. This role supports both internal team coordination and site-facing execution—keeping timelines sharp, data clean, and communication clear. This position may be performed remotely but requires flexibility and a willingness to travel as needed.

Responsibilities

• Support study execution by managing meeting logistics, documenting decisions, and tracking action items.
• Partner with Clinical Operations and site monitors to ensure protocol compliance and quality standards are met.
• Responsible for filing the site-level documents into the Trial Master Files (TMFs) in a timely manner.
• Track, review, and organize essential documents from sites and vendors.
• Identify, escalate, and help resolve site-level issues in collaboration with cross-functional teams.
• Assist with regulatory submissions and other study deliverables.
• Drive process improvements that enhance speed, quality, and patient impact.

Requirements

• Bachelor’s degree in a life science or health-related field, or equivalent industry experience.
• 5+ years of clinical trial experience in biotech, pharma, or CRO settings.
• Solid knowledge of GCP, ICH guidelines, and regulatory requirements.
• Exceptional organizational and communication skills.
• A proactive, problem-solving mindset with high attention to detail.
• Comfortable managing multiple priorities in a fast-paced, mission-driven environment.
• Strong team player who thrives in flat, agile organizations.
• Proficient in Microsoft Office (Word, Excel, PowerPoint, Outlook).

Work Environment

The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You’ll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Benefits

• 99% of the premium paid for medical, dental, and vision plans.
• Company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage.
• 401(k) matching dollar-for-dollar up to 6% on eligible contributions.
• Long-term stock incentives and Employee Stock Purchase Plan (ESPP).
• Discretionary quarterly bonus.
• Extremely flexible wellness benefit.
• Generous PTO, paid holidays, and company-wide shutdowns.

Pay

Annualized Base Salary: $75,000 USD - $95,000 USD

About the Company

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.