Human Resources Business Partner Senior Director, Data Technology & Engineering

General Summary

We are seeking a strategic, influential Senior Director, HR Business Partner to lead the people strategy for Vertex’s Data, Technology & AI (DTE) organization. This role partners closely with the Chief Digital & Information Officer (CDIO) and leadership team to translate business and technology priorities into an integrated talent and organizational agenda. The position plays a critical role in enabling execution of the Data/Technology/AI roadmap through leadership capability, operating model evolution, and enterprise talent strategy.

Strategic HR Partner

Serve as the primary HR partner to the CDIO and DTE leadership team, translating strategy into prioritized people and organizational initiatives and influencing executive decisions with data-driven insights.

Transformation Leadership

Lead large-scale change initiatives to embed and evolve the Data/Technology/AI operating model, ensuring effective adoption of new governance, decision rights, and ways of working.

Talent Strategy Ownership

Define and drive enterprise-wide talent strategies for DTE capabilities, including role architecture, skill frameworks, development pathways, and succession planning.

Strategic Workforce Planning

Develop strategies to attract, develop, and retain high-impact technical and leadership talent, leveraging build/buy/borrow approaches, internal mobility, and reskilling initiatives.

Executive Coaching & Leadership Development

Coach senior leaders and leadership teams to strengthen performance, decision quality, and alignment, while leading robust talent reviews and succession processes.

Culture & Engagement Leadership

Champion a culture of innovation, collaboration, and continuous learning, reinforcing organizational health, inclusion, and sustainable high performance.

AI & Analytics-Driven HR

Leverage analytics and AI to generate actionable talent insights, measure impact of HR strategies, and enhance decision-making, productivity, and outcomes.

Required Education

Bachelor’s degree required; advanced degree preferred

Required Experience

12+ years of progressive HR experience (or equivalent combination of education and experience), including significant partnership with senior leaders in complex, technology-enabled organizations

Required Knowledge, Skills & Capabilities

Deep expertise in organizational effectiveness, change leadership, and organization design

Strong understanding of Data/Technology/AI operating models and workforce implications of AI-driven transformation

Ability to leverage data, analytics, and AI to inform decisions and improve outcomes

Exceptional business acumen with the ability to connect talent strategy to business performance (speed, quality, risk)

Strong executive presence and influencing skills, with the ability to coach leaders through ambiguity and change

Agile, forward-thinking mindset with the ability to synthesize complex information into actionable strategies

Collaborative leadership style with high emotional intelligence, integrity, and resilience

Other Requirements

Ability to operate effectively in a fast-paced, complex, and evolving environment

Proven ability to lead through influence in a senior individual contributor capacity

Pay Range

$227,200 - $340,800

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status In this Hybrid-Eligible role, you can choose to be designated as: Hybrid: work remotely up to two days per week; or select On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com