Head of Global Manufacturing Science & Technology

About the role

Legend Biotech is seeking a Head of Global Manufacturing Science & Technology as part of the Manufacturing Science & Technology team based in Bridgewater, NJ. The Head of Global Manufacturing Science & Technology (MSAT) is the enterprise technical leader responsible for ensuring the robustness, scalability, capability, and continuous improvement of manufacturing processes across the product lifecycle. The role establishes the global MSAT strategy and provides technical leadership from late-stage development and technology transfer through commercial manufacturing and lifecycle management. The Head of Global Manufacturing Science & Technology ensures that manufacturing processes are scientifically understood, technically capable, operationally robust, scalable, and continuously improved to support reliable supply, product quality, patient needs, and business growth. As the enterprise technical authority for manufacturing processes, the Head of Global Manufacturing Science & Technology drives process robustness, technology transfer, process validation, continued process verification, technical investigations, manufacturing optimization, and advanced manufacturing capabilities across the global network. The incumbent will be a member of the GMS Leadership Team.

Responsibilities

• Global MSAT Strategy & Technical Leadership: Define and execute the global MSAT strategy and operating model aligned with business, portfolio, and manufacturing priorities. Establish global technical standards, capabilities, and governance for manufacturing processes across internal and external sites. Serve as the senior technical authority for process capability, robustness, scalability, and manufacturing performance.
• Process Technology & Manufacturing Performance: Own the technical strategy for process characterization, validation, process capability, continued process verification, and process monitoring. Drive consistency and systematic improvement of manufacturing processes to increase yield, reliability, capacity, throughput, consistency, and cost efficiency. Provide technical leadership for manufacturing investigations, process deviations, and recurring performance issues. Establish science- and data-based approaches to identify process risks and proactively improve manufacturing performance.
• Technology Transfer & Commercialization: Provide MSAT leadership for technology transfer and manufacturing readiness from development into commercial operations. Ensure effective transfer of process knowledge, control strategies, technical standards, and manufacturing capabilities into internal and external manufacturing networks. Partner with CMC and R&D to ensure development programs are designed for commercial scalability, manufacturability, and process robustness. Provide technical input to major manufacturing network, capacity, and commercialization decisions.
• Lifecycle Management & Continuous Improvement: Own the MSAT strategy for the technical lifecycle of commercial products, including process improvements, scale-up/scale-out, site transfers, capacity expansion, and manufacturing optimization. Identify and prioritize opportunities to improve quality, yield, throughput, cost, cycle time, and supply resilience. Lead implementation of advanced process technologies, automation, modeling, analytics, and digital manufacturing capabilities. Ensure manufacturing knowledge and process data are systematically leveraged to drive continuous improvement.
• Manufacturing & Global Network: Provide technical leadership, support and governance for MSAT activities at internal sites, CMOs/CDMOs and other external manufacturing partners. Ensure consistent technical standards, process understanding, technology transfer, and lifecycle management across the global manufacturing network. Partner with Manufacturing leadership to resolve technical, process, and performance issues.
• Innovation, Digital & Advanced Manufacturing: Establish the strategic roadmap for advanced manufacturing technologies, automation, digital manufacturing, process analytics, and data science. Accelerate adoption of