Head of Engineering

Compensation: $125K– $200K salary, up to 1.0% equity stock options Full benefits, including health coverage, PTO & parental leave About BiomeSense BiomeSense is a life sciences startup applying gut microbiome technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners. Role Summary Own the full hardware (HW) lifecycle for GutLab, from architecture & subsystem integration through manufacturing, validation & deployment for a complex electromechanical device & BOM. Act as final technical authority for GutLab system performance, fleet stability & next generation GutLabs (Gen3) production, combining hands-on engineering depth with strategic judgment to ensure current systems perform reliably in the field & Gen3 scales into manufacturing. Key Responsibilities System Ownership & Development: Own GutLab architecture (electromechanical & fluidic); lead design, testing & refinement via CAD, prototyping & manufacturingValidation & Deployment Readiness: Own validation, stage gates, documentation & traceability across revisions, firmware & field performance. Lead troubleshooting, diagnostics & closed-loop fixes to eliminate systemic failure modesEnd-to-End Execution: Set & execute high standards for all aspects of HW development: procurement, transfer, sustaining engineering & operationsManufacturing Scale-Up: Drive DFM, design freeze, pilot builds, supplier alignment, cost targets & manufacturing strategy + execution for Gen3Team Leadership: Mentor & lead a HW team; align resources, timelines & execution to production milestonesStrategic Problem Solving: Address any and all procurement challenges while identifying cost-effective solutionsCross-Functional Collaboration: Partner with other leaders to align hardware development with broader company strategy & goals Qualifications 8+ years’ experience in hardware engineering for complex electromechanical systemsDeep proficiency in CAD, tolerances, prototyping & manufacturingProduct lifecycle ownership (concept through transfer & scale-up)Proven ability to build & manage technical teamsSystems-level troubleshooting expertise across mechanical, fluidic & electronicStructured, decisive & execution-oriented with high accountabilityA strategic thinker who thrives under pressure in fast-paced environments This website uses cookies and other analytics technologies. By selecting "Allow", you consent to the recording, use and sharing of your website activity by this website and its service providers.