Head of DMPK
The Opportunity
Your work will change lives. Including your own.
The Opportunity
At Recursion we are redefining drug discovery by uniting industrial-scale data generation with sophisticated computational models. We are seeking a visionary Head of DMPK to join our leadership team.
You will lead the DMPK strategy to transition our internal and partnered programs from early hit-identification through to IND-enabling studies and early clinical development.
But this is not a traditional DMPK role. You will be a key architect in an environment that is pushing the boundaries of “predict more, test less” - bridging the gap between high-throughput, experimentally derived data generation and predictive modeling.
Who You Are
- The Academic Foundation: You hold a PhD (or equivalent) in Pharmacokinetics, Drug Metabolism, Pharmacology, or a related field.
- The Industry Veteran: You have a proven track record of moving multiple programs from Discovery into Development (typically 15+ years) in the pharmaceutical or biotech industry.
- The Nimble Mindset: You are comfortable working at the intersection of biology and technology. You are cautiously optimistic that data-driven, computational approaches are the future of drug discovery.
- The Modality Expert: Deep expertise in small molecule DMPK is essential. Experience with related modalities (ADCs, proximity-inducing or peptides) is a distinct advantage.
- The Regulatory Navigator: You are intimately familiar with IND submission requirements and have a history of successfully navigating regulatory interactions.
- The Collaborative Leader: You value "One Team" over silos. You are known for strong, transparent working relationships and the ability to influence cross-functional stakeholders.
Technical Skills & Expertise
- Expertise in in vitro & in vivo ADME as well as contemporary PK/PD modeling. Extending to the properties and data sets commensurate with CNS exposure (or conversely restricting exposure to peripheral tissues).
- Experience with human PK and efficacious dose prediction.
- Proficiency in managing CROs to ensure high-quality data and timely delivery.
- Knowledge of biotransformation and metabolic pathways.
- Extensive experience in working with external collaborators in all shapes and forms (CROs, SMEs, Large Pharma)
Working Location & Compensation
This is an office-based, hybrid position at any either of our offices located in Salt Lake City or New York City. Employees are expected to work in the office at least 50% of the time.
At Recursion, we believe that every employee should be compensated fairly. Based on the skills, experience, and qualifications needed for this role, the estimated annual base salary range is:
- New York City, Boston, & San Francisco Bay Area(s): $353,980–$443,080
- Salt Lake City & all other U.S. locations: $321,800–$402,800
In addition to base salary, this role is eligible for an annual bonus, equity compensation, and a comprehensive benefits package.