Head of Clinical Development & Strategy

Key Responsibilities

• Lead the definition and continuous refinement of Target Product Profiles (TPPs) for all early-stage assets.
• Ensure alignment between our AI/discovery capabilities and commercial/clinical viability.
• Define clear, stage-gated clinical and pre-clinical success criteria for every program in the Nosis Bio pipeline.
• Work seamlessly with the Director of Translation, Director of Chemistry, and ML team to ensure these milestones are met.
• Act as the lead clinical representative with our pharmaceutical partners.
• Co-develop and refine TPPs within these collaborations, deeply understanding partner objectives to guide them on the most clinically viable ways to deploy our targeted delivery technology.
• Identify, build, and maintain deep relationships with Key Opinion Leaders (KOLs) and clinical experts across our target indications to validate and refine our internal product strategy.
• Serve as clinical face of Nosis Bio.
• Represent our clinical strategy to external stakeholders, including institutional investors during upcoming fundraising cycles, partners, regulatory agencies, and the broader medical community.
• Partner tightly with the CTO and technical platform teams to ensure that our AI delivery and drug design outputs are constantly informed by real-world clinical constraints and endpoints.

Qualifications

• Education: MD or PhD required. MD/PHD ideal.
• Experience: 5+ years of strategic clinical development experience within the biotechnology or pharmaceutical industry, ideally with exposure to early-stage, fast-paced environments.
• Domain Expertise: Strong foundational understanding of targeted therapeutics; specific experience with RNAi/siRNA, or advanced drug delivery modalities is a significant plus. Significant experience across multiple, distinct therapeutic areas including fibrosis, immunology, neurology, and/or cardiometabolic disease.
• Strategic Chops: Proven track record of developing TPPs, shaping early-stage pipeline strategy, and defining clear go/no-go criteria for novel therapeutics.
• Collaboration Experience: Demonstrated ability to work alongside external clinical teams in pharma collaborations, helping to shape joint clinical strategy and maximize platform value.
• Communication & Clout: Exceptional ability to communicate complex clinical and scientific concepts to diverse audiences, from ML engineers to top-tier investors and pharma executives. A recognized presence capable of commanding respect from KOLs.