FDA Internship - Developing Assays to Characterize Outer Membrane Vesicle Based Vaccines (CMC)

About the role

The internship is focused on developing assays to characterize outer membrane vesicle based vaccines (CMC).

Responsibilities

• Utilize molecular epidemiology, genomics, animal models, and molecular microbiology to define mechanisms of Klebsiella pneumoniae pathogenesis.
• Contribute to the identification of potential targets for intervention including the development of vaccines and/or therapeutics.
• Define how K. pneumoniae evades detection by and/or modulates the host immune system.
• Investigate factors contributing to pathogenesis, gastrointestinal colonization, or antimicrobial resistance.
• Enhance practical experience in molecular microbiology techniques such as cloning, transposon library creation, and next-generation sequencing.
• Improve computational skills through sequence analysis and mathematical modeling.
• Develop proficiency in immunology-related techniques including ELISA, Western Blot, and Flow Cytometry.
• Enhance both oral and written communication skills, focusing on effectively conveying scientific concepts and findings.

Requirements

• Currently pursuing or have received a bachelor's degree in relevant fields within the past five years.
• Tissue culture, molecular cloning, whole genome sequencing and analysis, transposon sequencing, experience working with rodents, bioinformatics (Python, R), strong written and oral communication skills.
• Citizenship: U.S. Citizen Only.

Qualifications

• Life Health and Medical Sciences (51)

Skills

• Tissue culture
• Molecular cloning
• Whole genome sequencing and analysis
• Transposon sequencing
• Experience working with rodents
• Bioinformatics (Python, R)
• Strong written and oral communication skills

Benefits

No specific benefits are mentioned in the job posting.

Pay

The participant will receive a monthly stipend commensurate with educational level and experience.

Schedule

The appointment will initially be for one year, but may be renewed upon recommendation of FDA and is contingent on the availability of funds.

Contact Information

If you have questions, send an email to ORISE.FDA.CBER@orau.org. Please include the reference code for this opportunity in your email.

Application Process

To submit your application, scroll to the bottom of this opportunity and click APPLY.

Additional Information

A complete application consists of:

• An application
• Transcripts – Click here for detailed information about acceptable transcripts
• A current resume/CV, including academic history, employment history, relevant experiences, and publication list
• One educational or professional recommendation

All documents must be in English or include an official English translation.