FDA Immunogenicity Risk Assessment Fellowship

Research Project

The project will focus on generating In silico, In vitro and In vivo strategies to assess product immunogenicity risk of proteins, oligonucleotides and peptides.

Learning Objectives

• Under the guidance of the mentor, you will learn about the innate immune response modifiers.
• You will become proficient in In vitro and In vivo modeling.
• You will be encouraged to use state of the art technologies to analyze complex data.
• You will engage in critical mechanistic thinking that will enable you to become a mature scientist.

Mentor

The mentor for this opportunity is Mohanraj Manangeeswaran (Mohanraj.Manangeeswaran@fda.hhs.gov).

Anticipated Appointment Start Date

The anticipated appointment start date is 2026. Start date is flexible and will depend on a variety of factors.

Appointment Length

The appointment will initially be for one year, but may be renewed upon recommendation of FDA and is contingent on the availability of funds.

Level of Participation

The appointment is full time.

Participant Stipend

The participant will receive a monthly stipend commensurate with educational level and experience.

Citizenship Requirements

This opportunity is available to U.S. citizens, Lawful Permanent Residents (LPR), and foreign nationals. Non-U.S. citizen applicants should refer to the Guidelines for Non-U.S. Citizens Details page of the program website for information about the valid immigration statuses that are acceptable for program participation.

Qualification

The qualified candidate should have received a master's or doctoral degree in Immunology, Pharmacology, or Immunopathology. Degree must have been received within the past five years.

Preferred Skills

• Knowledge in the use of animal models and design of experiments (DOE) is preferred.

Application Instructions

To submit your application, scroll to the bottom of this opportunity and click APPLY.

Contact Information

If you have questions, send an email to ORISE.FDA.CDER@orau.org. Please include the reference code for this opportunity in your email.

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Background Investigation

Proof of health insurance is required for participation in this program. Participants do not become employees of FDA, DOE or the program administrator, and there are no employment-related benefits.

ORISE Education and Training Agreement

The participant will receive a monthly stipend commensurate with educational level and experience. The participant will receive a monthly stipend commensurate with educational level and experience.

FDA Ethics Requirements

The ORISE fellow’s obligation to protect and not to further disclose or use non-public information.