Executive Medical Director, Clinical Development Lead - Oncology

Position Summary

Cancer is unrelenting, but so are we. At GSK, we are committed to transforming outcomes for people with cancer through innovative science, bold ambition, and strong partnerships across the healthcare ecosystem. We focus our science where it can matter most — advancing care in cancers with high unmet need, grounded in a deep understanding of disease biology and deliberate scientific choices that connect discovery to meaningful impact in the real world.

Responsibilities

• Define and own the clinical strategy, scientific narrative, integrated benefit–risk position, and decision framework across the asset, ensuring a coherent and differentiated clinical position throughout the lifecycle
• Accountable for strategic outcomes across the asset, with study-level delivery, including design, execution, and data generation, led by Senior Scientists and programme teams within the CDL’s strategic direction
• Serve as the senior clinical strategy leader on the MDT core quad, acting as a full strategic partner to the Medicine Development Leader (MDL) and representing Clinical Development in portfolio, governance, and investment decisions
• Lead or co-lead governance and investment presentations to senior management, translating clinical evidence into clear strategic recommendations for portfolio prioritisation and progression
• Act as the recognised clinical authority and visible leader for the asset, ensuring its clinical vision, scientific identity, and development trajectory are clearly understood and advanced across the organisation
• Drive an integrated, end-in-mind approach to development, ensuring that target selection, development pathways, regulatory positioning, and commercial readiness are considered as a connected whole
• Leverage AI-enabled insights, advanced analytics, and emerging data platforms to inform asset-level strategic decisions and drive competitive advantage in development speed and decision quality
• Lead, develop, and mentor clinical development talent, contributing to talent calibration, succession planning, and capability building aligned to evolving development models

Qualifications

• Medical degree, PharmD, or PhD required
• Oncology clinical development experience in the pharmaceutical industry or relevant scientific, medical, or clinical experience
• Demonstrated experience operating at the asset, portfolio, or enterprise level, including governance and investment decision-making
• In-depth knowledge of GCP, ICH, FDA, EMA, NICE, and relevant regulatory frameworks
• Proven ability to lead and influence cross-functional teams in complex matrix environments
• Strong understanding of clinical development, oncology therapeutic landscapes, and drug approval processes
• Experience leveraging data, advanced analytics, or emerging technologies to inform clinical decision-making