Executive Director, Transformation & Integration Lead

About the Role

Jazz Pharmaceuticals is a global biopharma company dedicated to developing life-changing medicines for people with serious diseases. We are undertaking a bold, enterprise-wide transformation to reimagine our operating model and build a patient-centric, agile, and scalable rare disease organization. The Executive Director, Transformation & Integration Lead, is a senior leader responsible for setting direction and driving execution of mission-critical transformation programs that shape the future of Jazz. This role operates as a trusted advisor and strategic partner to senior leaders, designing, orchestrating, and embedding large-scale change across functions.

Responsibilities

• Enterprise Transformation Strategy & Vision:
  • Translate Jazz’s enterprise transformation vision into integrated, multi-year strategies, roadmaps, and value cases.
  • Partner with senior leaders to identify, prioritize, and shape transformation initiatives that drive organizational performance, growth, patient impact, and cost efficiency.
  • Define future-state operating models considering portfolio evolution, market dynamics, digital enablement, and organizational capabilities.
• End-to-End Integration and Transformation Leadership:
  • Serve as the accountable executive owner for integrations and key transformation programs, from concept through full-scale implementation and sustainment.
  • Lead complex integrations and initiatives spanning multiple workstreams, functions, and geographies, ensuring alignment to enterprise objectives and interdependencies.
  • Oversee the design and implementation of new ways of working, including structure, governance, decision rights, processes, incentives, capabilities, and technology.
• Executive Partnership & Influence:
  • Act as a thought partner and challenger to senior leaders, providing objective insight, rigorous analytics, and scenario-based recommendations.
  • Engage in productive challenge with Executive Committee (EC) members and functional leaders to drive alignment, resolve trade-offs, and accelerate decision-making.
  • Represent integration and transformation progress, risks, and outcomes to the EC and other senior governance forums.
• Change Leadership & Organizational Adoption:
  • Set the change agenda and ensure deep, lasting embedding of integration and transformation outcomes across Jazz.
  • Lead enterprise-wide change management strategies, including stakeholder engagement, communications, capability building, and cultural reinforcement.
  • Anticipate and actively manage resistance, enabling leaders and teams to adopt new mindsets and behaviors aligned with a customer- and patient-first orientation.
• Cross-Functional & Matrix Leadership:
  • Lead and develop matrixed integration and transformation teams and workstream leaders, fostering accountability, collaboration, and high performance.
  • Partner closely with executive leaders of assigned functions (e.g., R&D, Commercial, G&A, Digital) to ensure seamless integration and execution of transformation initiatives.
  • Model enterprise thinking and drive solutions that optimize outcomes for Jazz as a whole, not individual functions.
• Performance Management & Value Delivery:
  • Define enterprise-level KPIs, success metrics, and value realization plans linked to integration and transformation objectives.
  • Monitor progress rigorously, course correct as needed, and ensure delivery of committed outcomes.
  • Provide transparent, executive-level reporting on milestones, risks, and impact.

Qualifications

• Bachelor’s degree required; advanced degree (MBA, PhD, or equivalent) preferred.
• 12+ years of progressive leadership experience in life sciences, healthcare, management consulting, or enterprise transformation roles.
• Proven record of leading integrations in global pharmaceutical or biotech organizations for both assets in development and commercialized assets.
• Experience driving large-scale, complex, cross-functional transformations with measurable business impact.
• Demonstrated ability to operate credibly at the Executive Committee level, including preparing and delivering executive-level presentations.
• Deep expertise in one or more areas such as Commercial, R&D, G&A, digital transformation, operating model design, or enterprise change.
• Strong systems thinker with the ability to connect strategy, data, operating models, and culture.
• Highly effective influencer who works across silos and leads through ambiguity without direct authority.
• Exceptional analytical, strategic, and problem-solving capabilities.
• Experience with agile, design thinking, lean, or modern change methodologies strongly preferred.

Pay

For US-based candidates, the full and complete base pay range for this role is: $272,000.00 - $408,000.00. Individual compensation within this range will depend on factors such as qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The successful candidate may also be eligible for a discretionary annual cash bonus, equity grants, and comprehensive benefits, including medical, dental, vision insurance, 401k, and flexible paid vacation.