Executive Director, Early Clinical Development

About the role

The Executive Director of Early Clinical Development will lead the clinical development of Revolution Medicines’ molecules from early-stage studies to regulatory submissions and potential commercialization. This role requires extensive experience in clinical development, data analysis, and regulatory compliance.

Responsibilities

• Develop and execute comprehensive clinical development plans for Revolution Medicines’ molecules, ensuring alignment with scientific, regulatory, and commercial objectives.
• Lead, mentor, and manage a high-performing cross-functional team of clinical development professionals, fostering a culture of collaboration, innovation, and excellence.
• Oversee all aspects of clinical trial design and execution, including site selection, patient recruitment, data management, and regulatory compliance.
• Establish and maintain strong relationships with clinical investigators, regulatory agencies, and key stakeholders.
• Gather, analyze, and interpret clinical data, providing strategic insights to inform critical decisions and guide program development.
• Manage clinical development timelines effectively, ensuring efficient resource allocation and achievement of milestones.
• Stay abreast of the latest scientific advancements and regulatory trends in the field of clinical development.
• Partner with cross-functional teams, including research, regulatory affairs, commercial, and finance, to ensure seamless program execution and achieve shared goals.
• Manage multiple direct reports; potentially be a manager of managers.

Requirements

• MD, PhD or similar advanced biomedical graduate degree with 13+ or more years experience in pharmaceutical/biotech industry or academic background at the level of Associate Professor or higher.
• Extensive experience working with the principles and techniques of data analysis, interpretation, and clinical relevance as related to the pharmaceutical/biotech industry.
• Proven track record of successfully designing and conducting multiple clinical trials as part of a wider clinical development programs from early-stage to late-stage, direct experience with Phase 1 drug development.
• Experience authoring and clinical development strategy(ies) and bringing forward for governance.
• Extensive understanding of medical aspects of GCP (Good Clinical Practice), ICH (International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use), FDA, EMA, and other relevant guidelines and regulations.
• Proven experience to steer an IMP during its clinical development plan through major and varied Health Authority interactions (e.g. FDA, EMA, others).
• Has led Health Authority interaction(s).
• Strong orientation to teamwork. Excellent leadership, communication, and interpersonal skills, with the ability to inspire, motivate and mentor a diverse team.
• Expertise in building and maintaining strong relationships with internal and external stakeholders.
• Superb strategic thinking and analytical skills, with the ability to make data-driven decisions in a fast-paced environment.
• Able to recognize trade-off decisions and can determine priorities and goals.
• Outstanding written and business presentation skills.
• Experience publishing results of a clinical trial in a peer-reviewed journal is required.
• Proven ability to manage budgets and timelines effectively.
• Passion for innovation and a commitment to developing therapies that make a meaningful difference in patients' lives.

Qualifications

• MD, PhD or similar advanced biomedical graduate degree with 13+ or more years experience in pharmaceutical/biotech industry or academic background at the level of Associate Professor or higher.
• Extensive experience working with the principles and techniques of data analysis, interpretation, and clinical relevance as related to the pharmaceutical/biotech industry.
• Proven track record of successfully designing and conducting multiple clinical trials as part of a wider clinical development programs from early-stage to late-stage, direct experience with Phase 1 drug development.
• Experience authoring and clinical development strategy(ies) and bringing forward for governance.
• Extensive understanding of medical aspects of GCP (Good Clinical Practice), ICH (International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use), FDA, EMA, and other relevant guidelines and regulations.
• Proven experience to steer an IMP during its clinical development plan through major and varied Health Authority interactions (e.g. FDA, EMA, others).
• Has led Health Authority interaction(s).
• Strong orientation to teamwork. Excellent leadership, communication, and interpersonal skills, with the ability to inspire, motivate and mentor a diverse team.
• Expertise in building and maintaining strong relationships with internal and external stakeholders.
• Superb strategic thinking and analytical skills, with the ability to make data-driven decisions in a fast-paced environment.
• Able to recognize trade-off decisions and can determine priorities and goals.
• Outstanding written and business presentation skills.
• Experience publishing results of a clinical trial in a peer-reviewed journal is required.
• Proven ability to manage budgets and timelines effectively.
• Passion for innovation and a commitment to developing therapies that make a meaningful difference in patients' lives.

Skills

• Data analysis and interpretation.
• Strategic planning and execution.
• Regulatory compliance and oversight.
• Team leadership and mentorship.
• Communication and interpersonal skills.
• Strategic thinking and decision-making.
• Writing and business presentation skills.
• Leadership and management.
• Conflict resolution.

Benefits

Base Pay Salary Range: $265,000 - $331,000 USD

Our benefits package includes:

• Competitive cash compensation
• Rigorous equity awards
• Strong benefits
• Significant learning and development opportunities

Pay

Base Pay Salary Range: $265,000 - $331,000 USD

Schedule

Full-time position

Contact Us

If you have any questions about this position, please contact careers@revmed.com. For additional information regarding Revolution Medicines, visit our website at www.revmed.com.

Equal Opportunity Employer

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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