Early Development Team Leader

About the Company

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC Discovery Engine platform to engineer proteolysis targeting chimeras (PROTACs), designed to harness the body’s natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline, the company has three investigational clinical-stage programs: ARV-102 for neurodegenerative disorders, ARV-393 for relapsed/refractory non-Hodgkin Lymphoma, and ARV-806, a KRAS G12D PROTAC for solid tumors. The FDA recently accepted the New Drug Application (NDA) for vepdegestrant, an orally bioavailable PROTAC estrogen receptor degrader for ER+/HER2- advanced or metastatic breast cancer. Arvinas has also entered strategic partnerships with Pfizer and Novartis for the development and commercialization of its assets.

#TeamArvinas values diverse perspectives, innovation, and a mission-driven culture focused on pioneering therapies to improve patient lives.

About the Role

Arvinas is seeking a highly motivated and experienced Asset Team Leader to lead cross-functional teams responsible for the strategy and execution of early oncology development programs. The successful candidate will drive the strategy of early oncology assets, ensuring seamless execution against planned timelines. This role reports to the SVP, Asset Strategy and Team Leadership and can be remote, hybrid, or based at headquarters in New Haven, CT.

Responsibilities

• Lead cross-functional oncology asset teams and act as the main point of contact and program representative to executive management.
• Negotiate with and influence key internal and external stakeholders.
• Drive generation and execution of program strategy and Integrated Development Plans with a multidisciplinary matrixed team.
• Lead alignment on plans with governance and executive management to maximize long-term value for patients, physicians, payors, and Arvinas.
• Coordinate strategic and operational efforts with key functions, including Clinical Research, Clinical Operations, Regulatory, CMC, New Product Planning, and Project Management.
• Partner with Research to transition programs from exploratory research into development.
• Collaborate with functional leads to create and evaluate detailed scenario plans based on the external landscape and business needs.
• Manage and optimize timelines, financial accountability, and other vital metrics for multiple projects simultaneously.
• Work closely with the Project Manager on program progress, cost, resource allocation, timelines, and risk management.
• Drive team objective setting, prioritization, and performance to ensure adherence to plan and strategy.
• Proactively identify risks, resolve issues, and implement contingency planning.
• Foster a positive team environment to achieve high performance through trust, transparent communication, and consensus-building.
• Represent programs at governance and decision-making meetings.
• Lead and/or support corporate objectives, including Board meeting preparation, earnings preparations, and corporate presentations.
• Lead the External Engagement subteam.
• Supervise and mentor junior staff.

Qualifications

• Significant drug development leadership experience, with a history of managing cross-functional teams, external stakeholders, and partners, specifically in early oncology asset teams.
• Minimum of 15 years of relevant experience in pharmaceutical, academic, and/or medical research environments.
• Proven ability to lead and influence data-driven strategy planning and implementation.
• Strong decision-making skills and a proactive, strategic mindset.
• Ability to function effectively across a matrix organization with multiple stakeholders and drive team focus toward goals.
• Demonstrated experience in successfully leading teams, ensuring efficiency and on-target delivery.
• Strong interpersonal and communication skills, including presentation skills, with the ability to influence all levels cross-functionally.
• Excellent business acumen and judgment, with the ability to align teams to corporate strategy.
• Strong staff management and mentoring experience.
• Highly collaborative with outstanding relationship-building skills.

Arvinas will not provide VISA sponsorship for this position. Candidates must be able to work without current or future VISA sponsorship.

Work Environment

The duties of this role are generally conducted in a combination of company office and home office environments. Employees must be able to:

• Lift/carry 15/30 pounds unassisted/assisted (with or without accommodation).
• Work comfortably in a controlled environment with biological, infectious, and hazardous materials.
• Gown/degown PPE.
• Use a computer and engage in communications via phone, video, and electronic messaging.
• Engage in problem-solving, analysis, and dialogue.
• Collaborate with others and maintain availability during standard business hours.

Education

Ph.D., MD, or MBA, or an advanced degree in biomedical sciences or a discipline related to drug development.

Benefits

Arvinas offers a competitive package of base and incentive compensation, as well as a comprehensive benefits program designed to support the health, wellness, and financial security of employees and their families. Benefits include group medical, vision, and dental coverage, group and supplemental life insurance, and more.