Director, US Real-World Evidence and Health Outcomes – Oncology Pipeline

About the role

The role supports the US Pipeline Oncology Director in leading US Real World Evidence (RWE) & Health Outcomes Research (HO) strategy and execution for Oncology pipeline assets.

Responsibilities

• Evidence strategy and planning: Implementation of RWE/HO research by developing evidence generation plan and designing studies for 1–2 priority pipeline assets/indications, aligned to US medical, payer, and access needs; translate strategy into actionable workplans, timelines, and resourcing proposals.
• Study leadership (RWE/HEOR): Own day-to-day leadership for assigned real-world evidence and health outcomes studies (e.g., real-world evidence studies, cost-effectiveness/budget impact analyses, burden of illness, treatment patterns, patient-focused outcomes) including design and execution in partnership with internal functions and external vendors.
• Cross-functional stakeholder management: Support the US Pipeline Oncology Director in running cross-functional evidence strategy forums and asset-specific meetings by developing agendas/materials, surfacing options, documenting decisions, and tracking actions to closure.
• Scientific communication and quality: Draft/review project specifications, protocols, statistical analysis plans, study reports, abstracts, posters, and manuscripts; ensure adherence to SOPs and high scientific/operational quality.
• Trial design input for US relevance: Provide feedback to Clinical Development and cross-functional teams on optimal trial design to ensure enrollment of US-relevant patient populations and collection of endpoints/outcomes that support US stakeholder needs (e.g., health-related quality of life, patient-reported outcomes, resource utilization, and other health outcomes measures).
• Internal decision support: Provide RWE & HO input to internal decision-making during development and commercialization planning (e.g., trial design considerations, data gap assessments, value messages, evidence prioritization and sequencing).
• Marketed product support: Contribute 20% effort to US RWE & HO strategy and execution for a marketed product in endometrial and rectal cancer, including data generation planning, cross-functional alignment, and delivery of analyses/publications that support lifecycle evidence needs and value communication.
• External insight generation: Maintain strong alignment with Field Based Payer Medical Teams and other field stakeholders to obtain customer insights; incorporate insights into evidence plans and value communication needs.
• Vendor and budget management: Manage vendors and contractors for assigned studies, including scope, timelines, budget tracking, and change control; escalate risks/issues proactively.
• Governance, compliance, and capability building: Complete required training, adhere to company/department SOPs, and contribute to continuous improvement of processes that enable efficient planning, execution, and dissemination of RWE & HO deliverables.

Qualifications

• Master’s degree or PhD in health economics and outcomes research, epidemiology, public health, biostatistics, or related discipline.
• 3+ years’ experience within the pharmaceutical industry or academia related research within US Oncology experience.
• Designing a publication plan and having a presence of HEOR research studies at major clinical congresses.
• Experience managing multiple projects simultaneously.
• Expertise in HEOR and economic evaluation study designs/methods evidenced by publications and/or contributing to study concept sheets and protocols (including clear research questions, endpoints, data source selection, and bias/confounding mitigation), reviewing/authoring key sections of statistical analysis plans and study reports, and ensuring publication/disclosure readiness in accordance with internal SOPs and external requirements.
• Strong communication and presentation skills, demonstrated by developing and presenting clear, decision-oriented materials (e.g., evidence strategy slides, executive readouts) and summarizing outcomes/next steps for senior audiences.
• Proven ability to prioritize, pivot, and manage multiple projects simultaneously in a matrix environment.