Director - Targeted Protein Degradation

We need to output HTML fragment with sections: About the role? The posting includes mission description at start, then "What you will do" with subsections: Scientific and Strategic Leadership, Capability Building and Platform Innovation, Organizational Leadership. Then "What we expect of you" includes Basic Qualifications, Preferred Qualifications. Then "What you can expect of us" includes benefits, salary range note, total rewards plan details. Also there is mention of "The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted." No actual numbers given, so we cannot create Pay section because no specific numbers. Benefits: they list benefits: Retirement and Savings Plan, medical/dental/vision, life/disability, flexible spending, discretionary annual bonus, stock-based long-term incentives, award-winning time-off plans, flexible work models. Also mention "Total Rewards Plan". So we can create Benefits section with those details. Schedule: not mentioned. Pay: not specific numbers, so we should not create Pay section. Also we should not include boilerplate like EEO, accommodation, sponsorship, application deadline, etc. Also remove duplicated lines, navigation, cookie, etc. Also we should not repeat job title as heading. The page already shows it, so we don't add heading for "Director - Targeted Protein Degradation". We need to use

for section headings: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. But we should only include sections when there is real specific content. We have content for About the role (mission description). Responsibilities: we have "What you will do" with subparts; we can put that under Responsibilities. Requirements: maybe Basic Qualifications? But Requirements could be basic qualifications. Qualifications: maybe Preferred Qualifications? Or we could combine Requirements and Qualifications? The instruction says use those headings if content exists. We have Basic Qualifications (doctorate etc) and Preferred Qualifications. Could treat Basic as Requirements, Preferred as Qualifications. Also Skills: maybe we have skills like leadership, communication etc. Could put under Skills. But we need to avoid filler. Let's map: - About the role: mission paragraph(s) at start. - Responsibilities: the "What you will do" sections (Scientific and Strategic Leadership, Capability Building and Platform Innovation, Organizational Leadership). Could be a list of duties. - Requirements: Basic Qualifications (education + experience, managerial experience). - Qualifications: Preferred Qualifications (PhD, recognized leader, etc). - Skills: maybe we can extract skills: leadership, strategic vision, communication, influencing, collaboration, etc. But those are already in Preferred Qualifications. Could still make a Skills section summarizing those. However we must not invent or summarize away detail; we can list them as they appear. The Preferred Qualifications includes: Recognized scientific leader..., Deep understanding..., Experience establishing..., Strong understanding..., Demonstrated success..., Exceptional communication, influencing, and leadership skills... So we could put those under Skills. - Benefits: list of benefits as described. - Pay: not specific, so omit. - Schedule: not mentioned, omit. We must not include headings with filler. So we will output:

About the role

... mission paragraphs ...

Responsibilities

• Scientific and Strategic Leadership: ... (maybe break into subpoints? Could keep as one li with semicolons)
• Capability Building and Platform Innovation: ...
• Organizational Leadership: ...

But we need to preserve all substantive information; we shouldn't lose details. Could break each responsibility into multiple li items for each bullet inside. However the original text has paragraphs; we could keep as

inside each li? Simpler: each responsibility as a

maybe? But instruction: Use

• for any list of duties/requirements/benefits. So we need to make a list. We can split the responsibilities into separate li items each containing the paragraph text. Similarly for Requirements: Basic Qualifications: we can make a list: Doctorate degree and 4 years... OR Master's... OR Bachelor's... plus at least 4 years experience managing people/leadership. Could be two li: education requirement, managerial experience. Qualifications: Preferred Qualifications: list each bullet. Skills: maybe we can list skills from Preferred Qualifications: Recognized scientific leader..., Deep understanding..., Experience establishing..., Strong understanding..., Demonstrated success..., Exceptional communication, influencing, and leadership skills... Benefits: list each benefit. We must not include boilerplate like "As we work to develop treatments..." etc. That's part of "What you can expect of us" which leads to benefits. We'll extract benefits only. Let's craft. First, About the role: combine the mission paragraphs: "Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career." We need to preserve punctuation; but we can keep as is. Now Responsibilities: we have three big sections. Scientific and Strategic Leadership paragraph: "Build upon Amgen's differentiated Induced Proximity Platform to define and execute a long-term scientific vision for targeted protein degradation and proximity-based therapeutics, expanding the reach of the degrader platform into new biological spaces, therapeutic opportunities, and modalities while strengthening Amgen's leadership in next-generation drug discovery.Establish a differentiated scientific strategy that identifies where degradation and proximity-based mechanisms can uniquely address high-value biological targets and disease pathways beyond the reach of conventional therapeutic approaches.Drive innovation across the targeted protein degradation landscape, including molecular glues, heterobifunctional degraders, tissue-selective degraders, event-driven pharmacology, and emerging induced proximity modalities.Develop frameworks for identifying, evaluating, and prioritizing new biological opportunities enabled by targeted protein degradation and proximity biology.Anticipate emerging scientific, technological, and competitive trends and translate them into actionable platform strategies and capability investments.Serve as a key scientific advisor to Research leadership, influencing platform investments, capability development, and long-range innovation strategy.Foster a culture of scientific ambition, rigor, and innovation that expands the boundaries of what is considered druggable biology." Capability Building and Platform Innovation paragraph: "Define and build next-generation capabilities required to enable world-leading targeted protein degradation discovery, including chemical biology, proteomics, functional genomics, structural biology, computational biology, machine learning, and translational sciences.Champion the integration of AI- and data-driven approaches into target identification, ligand discovery, degrader design, mechanism elucidation, and prediction of therapeutic outcomes.Drive the development and adoption of novel experimental and computational technologies that accelerate discovery and deepen mechanistic understanding of induced proximity biology.Establish scalable scientific workflows and decision-making frameworks that enable efficient translation of emerging concepts into high-quality drug discovery opportunities.Identify capability gaps and proactively build internal expertise, external partnerships, and enabling technologies necessary to maintain scientific leadership in the field." Organizational Leadership paragraph: "Build, mentor, and develop a high-performing multidisciplinary team of scientists spanning chemical biology, protein degradation, chemistry, proteomics, and drug discovery.Foster a culture of collaboration, accountability, inclusion, and scientific excellence.Attract, develop, and retain exceptional scientific talent while creating opportunities for growth and leadership development.Enable a highly innovative environment where bold ideas are encouraged, rigorously evaluated, and translated into impactful scientific outcomes.Partner closely with Therapeutic Areas, Medicinal Chemistry, Research Informatics, Translational Sciences, Pharmacology, and Development organizations to maximize the impact of targeted protein degradation across the research portfolio.Drive alignment across functions to ensure efficient execution and translation of platform innovations into therapeutic opportunities.Identify and evaluate emerging scientific advances, enabling technologies, and partnership opportunities that strengthen platform differentiation and long-term impact.Cultivate a broad external network of scientific leaders and innovators to ensure early visibility into transformative advances across chemistry, biology, computation, and drug discovery.Represent the IPP organization in scientific, strategic, and executive forums, communicating a compelling vision for how induced proximity biology can create the next generation of transformative medicines." We'll put each as
• . Requirements: Basic Qualifications: "Doctorate degree and 4 years of scientific experience OR Master's degree and 8 years of scientific experience OR Bachelor's degree and 10 years of scientific experience In addition to meeting at least one of the above requirements, you must have at least 4 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above" We can split: Education requirement (the OR chain) and Managerial experience requirement. Qualifications: Preferred Qualifications list: - PhD in Chemical Biology, Biochemistry, Molecular Biology, Pharmacology, Medicinal Chemistry, or a related scientific discipline. - Recognized scientific leader with significant contributions to targeted protein degradation, molecular glues, induced proximity biology, or adjacent fields. - Deep understanding of degrader mechanisms, E3 ligase biology, chemical proteomics, structural biology, and translational pharmacology. - Experience establishing scientific strategies, building research capabilities, and driving organizational transformation. - Strong understanding of emerging computational and AI-enabled approaches in drug discovery. - Demonstrated success developing strategic external collaborations and evaluating innovative technologies. - Exceptional communication, influencing, and leadership skills with the ability to engage audiences ranging from scientific teams to executive leadership. Skills: Could be same as above? But we already used them as Qualifications. Perhaps we should not duplicate. Instead we could treat Qualifications as Preferred Qualifications and Skills as something else like "leadership, communication, strategic thinking". But to avoid duplication, maybe we omit Skills section and just have Requirements and Qualifications. The instruction says we can include Skills if we have content. We have content for skills (communication, influencing, leadership). But those are already in Preferred Qualifications. However we could still make a Skills section listing those specific skills: communication, influencing, leadership, strategic vision, etc. But that would be summarizing. Might be okay if we keep them as they appear. However we risk duplication. Better to not create Skills section if it would duplicate Qualifications. Let's see: The instruction: "Use

  for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule)." It gives examples but not mandatory to use all. We can choose which sections to include based on content. We have content for About the role, Responsibilities, Requirements (basic qualifications), Qualifications (preferred qualifications), Benefits. That's enough. We'll omit Skills. Now Benefits: list: - Retirement and Savings Plan with generous company contributions - Group medical, dental and vision coverage - Life and disability insurance - Flexible spending accounts - Discretionary annual bonus program (or for field sales representatives, a sales-based incentive plan) - Stock-based long-term incentives - Award-winning time-off plans - Flexible work models where possible Also mention "Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities". Could include that as a summary but we already list specifics. We'll include the list. We must not include the sentence about "The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors..." because no specific numbers, so we omit Pay