Director, Statistical Programming

This role sits within the Early Oncology Programming group and is accountable for a large and diverse portfolio of products spanning phase 1/2 trials across various mechanisms of action and multiple oncology indications.

About the Role

As Statistical Programming Director, you will provide strategic programming leadership and line management within Onc Biometrics, collaborating with global product development teams. You will manage and mentor a group of programmers who are accountable for efficient delivery on studies that are both outsourced and delivered internally, ensuring high quality of deliverables while complying with AstraZeneca and industry standards, SOPs, and GxP requirements. You will also be part of the larger programming leadership team within oncology programming, responsible for activities beyond clinical trials, such as providing strategic or SME contributions on cross-functional teams to deliver continuous improvement, innovation, and automation solutions.

Responsibilities

• Provide strategic programming leadership and line management within Onc Biometrics
• Manage and mentor a group of programmers accountable for efficient delivery on outsourced and internally delivered studies
• Ensure high quality of deliverables while complying with AstraZeneca and industry standards, SOPs, and GxP requirements
• Collaborate with global product development teams
• Provide strategic or SME contributions on cross-functional teams to deliver continuous improvement, innovation, and automation solutions
• Manage and lead regulatory submissions
• Solve problems, recommend process improvements, and execute process improvements
• Lead and influence teams and work with cross-functional teams including Data Management, Biostatistics, Epidemiology, Clinical Operations, and Pharmacovigilance to initiate, lead, and execute new initiatives and process improvements

Essential Skills/Experience

• Minimum bachelor's degree in mathematics (e.g., Applied Math, Engineering, etc.), Statistics, Computer Science, Life Science, Public Health, or equivalent experience
• Minimum 10 years of experience with advanced knowledge of the clinical development process and industry standards
• 7+ years people and/or project management experience
• Advanced SAS programming skills in a clinical and statistical data environment
• Demonstrated programming leadership capability with ability to develop teams and individuals and lead them toward a common goal
• Demonstrated influencing, planning, and organizational skills
• Ability to provide input to functional strategies
• Strong project management skills and experience with scope management, resource management, financial management, project planning, and resource allocation
• Significant experience in leadership capacity with a focus on identifying, leading, and advancing talent
• Experience working in a clinical development organization with a heavy emphasis on support of multiple, ongoing projects
• Thorough understanding of pharmaceutical clinical development (i.e., understanding of statistical concepts, techniques, and clinical trial principles)
• Thorough understanding of industry standards such as CDISC and 21 CFR Part 11
• Strong ability to solve problems, recommend process improvements, and execute process improvements
• Ability to lead and influence teams
• Excellent verbal and written communication skills in a global environment
• Proven ability to work with cross-functional teams, specifically Data Management, Biostatistics, Epidemiology, Clinical Operations, and Pharmacovigilance
• Recognize behaviors that align with our values critical to the success of our employees, mission, and business objectives

Desirable Skills/Experience

• Broad experience, ideally across multiple therapeutic areas and outside of the field of Statistical Programming
• Previous oncology experience, ideally in both heme and solid tumor
• Knowledge/experience using open source and/or AI in Statistical Programming
• Experience in regulatory submissions and interactions
• Demonstrated experience designing and implementing business processes
• Willingness and ability to travel

Pay

The annual base pay for this position ranges from $168,830.40 – $253,245.60 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles, and commissions for sales roles.

Benefits

• Qualified retirement programs
• Paid time off (i.e., vacation, holiday, and leaves)
• Health, dental, and vision coverage in accordance with the terms of the applicable plans

Why AstraZeneca

Here, ambitious science meets real-world impact. You will work in an environment that pairs cutting-edge platforms—multi-omics, single-cell and spatial technologies, AI/ML, and advanced imaging—with a pipeline that moves decisively from discovery to the clinic. We bring diverse specialists together to ask bold questions, pressure-test ideas, and accelerate progress against some of the hardest-to-treat cancers, valuing kindness alongside ambition so you can stretch your skills while making a tangible difference for patients.

Date Posted: 09-Sep-2026 | Closing Date: 17-Sep-2026