Director/Sr. Director, Commercial Production Management (CPM) Strategy

About the role

The Director/Sr. Director, Commercial Production Management (CPM) Strategy & Supplier Relationship Management, is accountable for defining and governing the company’s strategy for external Clinical and Commercial Contract Manufacturing Organizations (CMOs). The role provides objective, portfolio-level oversight, converts performance and risk information into strategic priorities, and ensures that CMO partnerships support reliable supply, quality, cost, and business continuity. This position establishes the CMO governance model, leads business reviews, oversees strategic initiatives and contract performance, provides integrated reporting to GSM leadership, and leads assigned SRM resources and cross-functional governance teams. SRM is a core pillar of the broader CPM Strategy mandate. This position is also responsible for MSAT activities for drug products/finished drug products to CMOs and will be leading a team to execute technology transfer activities to CMO sites for NDA submission support and commercialization of SKLSI products.

Responsibilities

• Develop and maintain the enterprise CMO operating strategy for clinical and commercial supply, aligned with GSM, product, quality, and business priorities.
• Establish and oversee a consistent governance framework for CMOs, including decision rights, escalation pathways, review cadence, performance standards, and accountability for follow-through.
• Lead periodic CMO business reviews and executive governance forums; ensure decisions, commitments, risks, and corrective actions are documented and closed on schedule.
• Translate portfolio performance and risk trends into prioritized strategic initiatives, resource recommendations, and management decisions.
• Provide strategic oversight of CMO contracts and service commitments in partnership with Global SCM, Procurement, Legal, Finance, Quality, and business owners.
• Own the SRM framework and serve as the strategic relationship lead for designated CMOs, promoting transparent, fact-based, and mutually accountable partnerships.
• Define standardized scorecards and key performance indicators across quality, delivery, service, cost, and responsiveness, including OTIF, RFT, lead time, deviations, complaints, CAPA effectiveness, release readiness, and Cost of Poor Quality (CoPQ).
• Evaluate CMO performance objectively across the portfolio, identify systemic trends, benchmark performance, and prioritize improvement opportunities.
• Ensure performance expectations are understood by internal stakeholders and CMOs and that improvement commitments are integrated into business-review and governance routines.
• Maintain an integrated view of CMO supply, quality, capacity, compliance, contractual, and business-continuity risks; establish early-warning indicators and risk-based escalation criteria.
• Coordinate mitigation plans with CPM Operations, MSAT, Global SCM, Quality, Regulatory, and other functions; track ownership, milestones, residual risk, and closure effectiveness.
• Provide portfolio-level oversight of deviations, complaints, CAPAs, change controls, quality agreements, lead-time performance, and recurring operational issues without replacing functional Quality authority.
• Lead or sponsor cross-functional root-cause analysis for recurring or systemic issues and ensure preventive actions are translated into sustainable operating improvements.
• Lead strategic CMO initiatives such as governance redesign, performance recovery, network optimization, capability development, risk reduction, and partnership improvement programs.
• Develop integrated dashboards and executive reports that summarize CMO performance,