Jobs · Legal · California

Director, Regulatory Affairs (Global Filing Lead)

Revolution Medicines · San Francisco Bay Area · 1 wk ago
HybridLegal$211k–$264k/yrFull-time

The Opportunity

The Director of Regulatory Affairs (Global Filing Lead) is accountable for driving preparation & execution of global regulatory NDA/MAA filings for late-stage oncology programs at RevMed. They will manage end-to-end execution of the dossier, ensuring cross-functional coordination and effective communication across Regulatory, Clinical, Biostatistics, CMC, Quality, Translational Medicine and Commercial.

The Director will support drug development teams and ensure delivery of targeted, pragmatic, well-vetted, consistent and actionable regulatory advice.

Required Skills, Experience and Education

  • Degree in life sciences, pharmacy, medicine, or related fields with a minimum of 12 years in the pharmaceutical/biotech industry or relevant work experience and a minimum of 8 years in Regulatory Affairs including a regulatory strategy role.

  • Proven success in executing global NDA/MAAs (preparation, submission & approval).

  • Experience filing applications under expedited filing pathways and programs to enable fastest possible regulatory approval.

  • Demonstrated ability to lead Health Authority interactions and negotiations.

  • In-depth knowledge of CTD structure and management of dossier components.

  • Direct experience in oncology drug development including oversight of large, global Phase 3 registrational studies.

  • Flexibility to support business needs of dynamic registrational programs.

  • Skilled at representing Regulatory on cross-functional teams and presenting to senior leadership.

  • Excellent communication, planning, and organizational skills with the ability to manage multiple projects and tight deadlines.

Preferred Skills

  • Prior experience with regulatory filings and strategy in APAC and access consortium countries highly preferred.

  • An advanced degree is desirable.

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