Jobs · OTHR · Massachusetts

Director, Real-World Evidence (RWE) Scientist — Oncology

Barrington James · Boston, MA · 2 wk ago
OTHRFull-time
About The Role We're looking for a true epidemiologist with deep RWE expertise who can move fluidly between strategy and hands-on execution, leading evidence generation for rare tumour assets end to end, from designing non-interventional studies (NIS) through to regulatory-facing evidence packages. This is not a pure strategy role, and it's not a pure execution role: you'll need to want, and be capable of, both. What You'll Do Lead RWE strategy and end-to-end execution for rare tumour assetsDesign and scope non-interventional studies (NIS), including defining the right endpoints and evidence questionsOwn external control arm strategy and evidence generationSource, evaluate and select vendors to support studiesLead regulatory-facing interactions and evidence generation — this role interfaces with regulatory and clinical development, not payersPresent project strategy directly to the project strategy team and to global product team leaders and product headsTranslate complex, methodological RWE concepts into clear, digestible input for cross-functional stakeholdersCollaborate closely with adjacent quantitative functions — clinical measurable sciences, data science, and the broader patient-focused evidence team — in a highly collaborative, flat-structured environment What You'll Bring A genuine epidemiology background with strong real-world evidence (RWE) expertiseExperience in non-interventional study (NIS) design, external control arms, evidence generation, and regulatory scienceOncology or rare disease experience is essentialA demonstrated ability — and desire — to operate across both strategic and hands-on/execution work; candidates seeking a purely strategic remit, or who are only comfortable executing without strategic input, won't be the right fitStrong communication skills, with the ability to simplify methodologically dense material for varied audiencesComfort working directly with senior product and clinical development stakeholders

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