Director, R&D FP&A

The Impact You’ll Have

Strategic Partnership & Decision Support
Partner with R&D leadership and project teams to develop portfolio and program-level financial plans.
Lead scenario modeling, cost-benefit analyses, and vendor investment decisions.
Support clinical program investment decisions and other high-priority strategic initiatives.
Financial Planning & Analysis
Deliver accurate and timely forecasts, budgets, and long-range plans for R&D functions.
Prepare and present financial analyses to senior leadership, including materials for Board meetings.
Provide variance analysis and actionable insights to inform decision-making.
Cross-Functional Collaboration
Partner closely with Accounting to align budget vs actuals, including accruals, coding, and variance reporting.
Collaborate with functional stakeholders to translate scientific and operational plans into financial outcomes.
Process Improvement & Systems
Drive improvements in FP&A processes, reporting, and forecasting accuracy.
Partner with the Head of FP&A to enhance and automate allocation methodologies across programs and indications.

Leadership Competencies

• Communication and Influence - Builds communication channels across Maze for sharing information. Influences Senior Management decisions through persuasive arguments. Respectsfully addresses differing opinions leading to support of decisions.
• Teamwork and Collaboration - Champions partnerships and connections across Maze. Proactively addresses issues that could result in breakdown of team relationships. Spotlights team and individual contributions in public forums.
• Execution and Results - Addresses gaps and leverages strengths to get best results. Maintains a steadying presence and clarifies priorities during change. Anticipates and removes barriers that put functional/corporate goals at risk.
• Develop Others and Self - Removes barriers to staff development and empowers them to make their own decisions. Stays current on industry trends and keeps direct-reports prepared and responsive.

What We’re Looking For

• Experience & Background - Bachelor’s degree in Finance, Accounting, Economics, or related field; MBA or equivalent experience preferred. 10+ years of experience in the pharmaceutical or biotech industry, including significant FP&A experience. Experience supporting R&D or development organizations strongly preferred. Clinical trial forecasting and accruals experience preferred.
• Technical & Analytical Skills - Advanced proficiency in Excel and PowerPoint. Experience with financial systems such as NetSuite, Coupa, and Anaplan, or similar tools. Strong financial modeling and forecasting capabilities, including ad hoc analysis.
• Business Partnership & Communications - Proven ability to build strong relationships and influence cross-functional stakeholders. Ability to translate complex scientific and strategic concepts into clear financial insights. Excellent written and verbal communication.
• Execution & Mindset - Highly organized with the ability to manage multiple priorities and meet deadlines. Detail-oriented and solution-driven, with a focus on continuous improvement. Collaborative mindset with a focus on improving efficiency and effectiveness. Interest in exploring applications of AI to enhance FP&A processes.

About Maze Therapeutics

Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1-mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work.

Core Values

• Further Together - Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.
• Impact Obsessed - We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
• Stand True - Our integrity is foundational; it guides us no matter the obstacle.

Job Details

• Hybrid Scheduled - Two-to-three days per week in office.
• Location - South San Francisco, CA.
• Annual Salary Range - $227,000 to $277,000.
• Eligible for Annual Performance Bonus.
• Benefits Package - Competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match, and a generous holiday and PTO policy.