Director, Quantitative Systems Pharmacology
About the role
For our client, we are seeking a Director, Quantitative Systems Pharmacology to join the team of a leader in the Pharmaceuticals & Biotech space. This leader will oversee quantitative systems pharmacology strategy and modeling efforts that inform drug discovery and clinical development. The role will focus on building and applying mechanistic models to better understand disease pathways, drug effects, and target interactions, with a particular emphasis on neurology-related programs. This position will partner closely with cross-functional stakeholders to strengthen model-informed drug development and support critical dose selection decisions.
Location: Remote - US based candidates only, no visa sponsorship available
Responsibilities
- Develop and apply QSP models to understand disease pathways and drug effects
- Enhance existing QSP platforms to reveal drug-target interactions
- Lead preclinical and clinical QSP strategies for dose selection
- Advocate for and integrate model-informed drug development approaches
- Collaborate with cross-functional teams to advance QSP capabilities
- Manage timelines and expectations for modeling and simulation work
- Analyze large datasets to uncover causal relationships in drug responses
Qualifications
- PhD, MD-PhD, or PharmD in a quantitative discipline such as Bioengineering, Systems Biology, or a related field
- Expertise in applied mathematical modeling and numerical methods
- Experience in quantitative systems pharmacology and mechanistic modeling
- Proven track record in drug discovery or clinical development using QSP
- Strong knowledge of pharmacology, physiology, and disease mechanisms
Benefits
- Participation in the Annual Incentive and Long Term Incentive Plans
- Access to comprehensive employee benefit programs
- Potential for additional unspecified benefits
Pay
$208,200 – $273,200 annually