Director of Translational Science

Director of Translational Science

We're looking for a Director of Translational Science to work directly with our patients and their care teams to translate complex molecular profile data into clear, evidence-based treatment options. This is a non-traditional translational science role where you'll operate at the intersection of oncology, molecular genomics, and clinical evidence interpretation.

• Key Responsibilities:
• Prioritize SOC, trials, and other therapeutic options (including off-label/expanded access when appropriate) based on patient molecular data and clinical evidence
• Interpret evidence with rigor: Synthesize trial data, biomarker subgroup performance, and real-world feasibility to evaluate therapeutic options
• Communicate with patients: Present findings directly to patients and their care teams, answer their questions, and help them think through next steps
• Partner with computational biology: Work with our computational biologists to integrate and synthesize patient molecular data (variants, expression, scRNAseq, IHC/mIF as relevant)
• Coach team members: Oversee one or more supervisees, providing regular coaching and partnership to ensure that they deliver expert, accurate analysis to our patients
• Contribute to internal knowledge bases: Draft therapy/biomarker evidence summaries, indication briefs, trial digests, and interpretation playbooks for use by the scientific team
• Help guide R&D efforts: Work with scientific, engineering, and product teams to help develop Valius's scientific offering

Requirements

• Advanced degree or equivalent experience in a relevant discipline (with substantial oncology experience)
• Deep understanding of oncology therapeutics (targeted therapy, immuno-oncology, ADCs, resistance, sequencing, tumor-type nuance)
• Demonstrated strength interpreting clinical trial evidence and explaining clinical relevance (including biomarker subgroups)
• Experience presenting complex information to patients confidently, clearly, and empathetically
• Excellent written and verbal communication
• Comfort working in a high-stakes, client-facing setting
• Comfort working with ambiguity and evolving evidence in fast-moving therapeutic areas
• Commitment to our patient-focused mission
• Interest in working for a small, early-stage startup

What You'll Bring

• Strong oncology fluency across modalities and tumor types
• A deep understanding of the oncology therapeutic landscape
• Expert ability to interpret clinical trial evidence and apply it to real-world patient contexts
• Exceptional communication skills with patients, clinicians, and scientists across disciplines

What We'll Bring

• Competitive salary and equity compensation
• Generous refresh grants
• Comprehensive benefits (health, dental, vision, 401(k))
• Genuine investment in your professional development
• Funny, mission-driven team culture