Core Facility Research Mgr/Dir - CCOM Viral Vector Core
About the role
The Carver College of Medicine (CCOM) is seeking a Core Facility Research Manager/Director to serve as the Technical Director for the Office of Research Viral Vector Core. This position provides scientific and technical leadership in the management, design, and execution of the Viral Vector Core research support facility, with a focus on vector production.
Responsibilities
Serve as the frontline scientific, technical, and administrative leader of the Viral Vector Core, providing expertise in the operation of a core research facility.
Interact with investigators to support new projects and provide technical guidance in specialized areas of research.
Manage HDAd production, including project communication, cell culture, transfection, vector amplification, purification, and quality control assays.
Oversee and assist, as needed, with AAV, lentiviral, Ad5, and vaccinia vector production.
Oversee or conduct experiments, simulations, or theoretical investigations, and independently develop new experimental methods to support the facility’s strategic plan and advance research activities.
Stay current with developments in vector production through ongoing literature review.
Seek collaboration and expertise from investigators in the field as needed.
Review production data in detail when troubleshooting issues arise.
Oversee high-level management of all projects within the vector core and review projects prior to shipping and closure.
Develop new data analysis techniques or methodologies.
Provide daily functional supervision and orientation for new staff members and advanced training on equipment, vector purification, and quality control procedures.
May present educational courses or seminars in areas of expertise.
Provide technical consultation within the full-service core facility.
At the request of investigators, review methods sections of research papers related to the core facility’s specialty prior to publication submission.
Serve as the primary contact for acquiring equipment quotes, determining specifications, and procuring parts and services.
Supervise installation of new equipment.
Test new equipment to ensure it meets specifications before authorizing payment.
Troubleshoot equipment failures, procure repair parts, implement repairs, supervise field service engineers and facility staff, and test equipment after repairs to ensure proper function.
Determine specifications for upgrading or purchasing new instruments and implementing new specialized services.
Develop and implement maintenance schedules, procedures, and techniques.
Perform or supervise preventive maintenance on instrumentation and equipment.
Aid the Department of Facilities Management in specifying, implementing, and supervising facility modifications or upgrades.
Ensure facility and equipment comply with safety regulations and University Environmental Health and Safety standards.
Develop and manage operational systems such as billing programs, facility reservation systems, data servers, and data backup and archiving systems.
Optimize the use of facilities and equipment.
Remain current on emerging techniques, software programs, and instrumentation in the field.
Conduct cost analyses and determine service charges for the Viral Vector Core.
Update the online catalog and website with new information and pricing.
Manage billing, shipping, and other financial aspects of the core.
Oversee operational, fiscal, and HR/staffing activities of the facility.
Prepare and manage budget expenditures.
Prepare “state-of-the-facility” reports and presentations for the university, college, or external research funding agencies.
Develop and manage internal and external communications, including print and web-based materials.
May write or assist with research proposals or grants to secure funding for new instrumentation and techniques that enhance the core facility’s research capabilities.
Hire, manage, and evaluate staff.
Support staff development, prepare promotion materials, and provide consultation to the Director during annual reviews.
Manage the annual Environmental Health and Safety (EHS) review and ensure the laboratory and staff remain compliant with safety requirements.
Qualifications
Masters degree in an appropriate field or an equivalent combination of education and experience is required.
A minimum of five years or related experience.
Demonstrate job-related experience with fostering a welcoming and respectful work environment and/or otherwise demonstrate their ability to foster a welcoming and respectful work/academic environment for people from all types of backgrounds.
Excellent written and verbal communication skills.
Ability to work independently and as part of a multidisciplinary team.
Familiarity with broad virus families.
Experience with production of viruses and viral vectors.
Desirable Qualifications
PhD in Microbiology, Virology, or related field.
Experience with Virus Engineering.
Experience with optimization of protocols.
Experience with quality control measures.
Demonstrated innovation with viral engineering.
Familiarity with University of Iowa Policies and Procedures.
Prior supervisory experience.