Computational Biologist - Protein Engineering

About the role

We’re looking for a computational biologist to help us curate, build, and scale a comprehensive set of drug discovery tools. You will work directly with the founders to build and deploy tools for structure prediction, protein design, docking, scoring, and more. You’ll be working directly with customers to help them leverage the best open source software for their task, often chaining multiple tools together.

Responsibilities

• Work directly with the founders to build and deploy tools for structure prediction, protein design, docking, scoring, and more.
• Help customers leverage the best open source software for their task, often chaining multiple tools together.
• Collaborate with other team members to develop and refine computational tools for drug discovery.
• Contribute to the curation and maintenance of a comprehensive set of drug discovery tools.

Requirements

• Knowledge of ML and physics based tools in structural biology, protein design, molecular dynamics, protein-protein and protein-ligand docking, peptide discovery, virtual screening, etc.
• Familiarity with literature and evolving state of the art in computational protein engineering tools.
• AWS DevOps (DynamoDB, EC2, S3, docker, etc.) and MLOps (CUDA, conda, TensorFlow, PyTorch).
• Ability to develop general purpose, production-ready software.
• Located in the SF Bay Area or able to relocate to the Bay Area.

Qualifications and Skills

• Knowledge of ML and physics based tools in structural biology, protein design, molecular dynamics, protein-protein and protein-ligand docking, peptide discovery, virtual screening, etc.
• Knowledge of enzymology, protein therapeutics, and peptide discovery.
• Familiarity with literature and evolving state of the art in computational protein engineering tools.
• AWS DevOps (DynamoDB, EC2, S3, docker, etc.) and MLOps (CUDA, conda, TensorFlow, PyTorch).
• Ability to develop general purpose, production-ready software.
• Likely located in the SF Bay Area or able to relocate to the Bay Area.

Pluses

• Experience developing machine learning models for proteins (language models, structure prediction, design).
• Knowledge of full stack software engineering, e.g. React and API development.
• Computational chemistry, including molecular dynamics, docking, and virtual screening methodologies for small molecule discovery.
• Graduate degree in math, CS, stats, bioengineering, comp bio, or a related field.