Clinical Variant Scientist - Pathology & Immunology
Location: St. Louis, MO 63108
About the role
The Clinical Genomics Laboratory is an academic clinical laboratory that provides a range of tests enabling the diagnosis, treatment, and monitoring of inherited and acquired genetic conditions. This position supports clinical genomic testing workflows for diagnosing suspected constitutional or germline conditions through targeted gene panels and genome-scale sequencing. It also supports clinical education initiatives and translational research, focusing on genetic variant analysis, curation, and interpretation.
Participates in:
- Evaluation of new tools and platforms
- Clinical test development and validation
- Production of standard operating procedures and scholarly/educational materials
- Facilitating regulatory compliance
Responsibilities
- Analyze, assess, and interpret genetic variation identified via clinical genomic testing workflows (targeted and comprehensive genomic testing).
- Analyze and integrate complex information from multiple sources to determine applicability of identified genetic variation to clinical care.
- Interpret genetic variation in accordance with up-to-date professional society guidelines.
- Assess quality control metrics as they relate to next generation sequencing and variant interpretation.
- Aid clinical staff, residents, and fellows with conducting variant interpretation.
- Develop, implement, and evaluate information, tools, and processes to assist clinical faculty/staff with clinical genomic testing, variant analysis/interpretation, and reporting.
- Work with clinical genomics test development, improvement, optimization, validation, and assurance of regulatory compliance.
- Aid with maintaining standard operating procedures for clinical genomic workflows.
- Support clinical and research faculty/staff with translational research projects.
Requirements
- Master's degree (required)
- Ph.D. in a relevant field (preferred)
- Three years of relevant experience
Skills
- Analytical Processes
- Analytical Thinking
- Biology
- Clinical Databases
- Clinical Laboratory Operations
- Communication
- Data Security
- Deadline Management
- Detail-Oriented
- Genetic Research
- Group Problem Solving
- Integration Management
- Microsoft Office
- Next Generation Sequencing (NGS)
- Next Generation Sequencing Data Analysis
- Organizing
- Prioritization
- Process Optimization
- Scientific Literature
- Stress Management
- Team Collaboration
- Working Independently
Schedule
This position follows a Sunday–Thursday work week. It is preferred that the incumbent works on-site at the Washington University School of Medicine; however, remote work will be considered.
Pay
Salary range: $77,700.00 – $120,400.00 annually.
Benefits
- Up to 22 days of vacation, 10 recognized holidays, and sick time
- Competitive health insurance packages with priority appointments and lower copays/coinsurance
- Free Metro transit U-Pass for eligible employees
- Defined contribution (403(b)) Retirement Savings Plan with university contributions starting at 7%
- Wellness challenges, annual health screenings, mental health resources, mindfulness programs, employee assistance program (EAP), financial resources, and access to dietitians
- 4 weeks of caregiver leave to bond with a new child
- Family care resources for childcare and adult care needs
- Tuition coverage for employees and their families, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years