Clinical Research Coordinator - Duke Cancer Institute

About the role

The Duke Cancer Institute (DCI) is seeking a Clinical Research Coordinator to support an operationally complex research study within the Cancer Control and Population Sciences Clinical Research Program (CCPS). This position is housed within the Oncology Clinical Research Unit (CRU) and supports high-impact cancer research that directly engages adult participants through electronic consent, surveys, and biospecimen collection.

Responsibilities

• Coordinate and manage study operations by implementing recruitment and retention strategies, evaluating enrollment feasibility, maintaining participant engagement, and identifying barriers to participation while proposing and implementing solutions across the study lifecycle.
• Recruit, screen, consent, and support participants by working closely with the Principal Investigator and study team; independently conduct and document consent, schedule and conduct study visits, manage repeated participant outreach and follow-up, and ensure accurate tracking of participant progress across multiple participation pathways.
• Ensure regulatory compliance and study integrity by maintaining regulatory binders, enrollment logs, and system documentation; recording and promptly reporting adverse events; assisting with Delegation of Authority Logs, COI documentation, Data Safety Monitoring Plans, and Duke Research Data Lifecycle requirements.
• Manage and protect study data by accurately entering data into EDC systems, identifying and resolving data discrepancies, investigating missing or incomplete documentation, and ensuring compliance with institutional policies related to data security, provenance, and confidentiality.
• Serve as a key communication and leadership resource by acting as the primary liaison among sponsors, investigators, and study personnel; escalating issues appropriately; supporting onboarding and training of research staff; sharing research updates; and contributing to continuous improvement of research processes.

Requirements

• Completion of an Associate’s degree
• Two years of relevant research experience
• Completion of the DOCR North Carolina state-approved Clinical Research Apprenticeship program may substitute for one year of experience
• Ability to effectively use standard computing software and web-based applications (e.g., Microsoft Office products and internet browsers)

Preferred Qualifications

• Experience with human subjects research, including informed consent, confidentiality, and adherence to IRB-approved protocols
• Strong participant-facing communication skills, including conducting outreach and follow-up via phone and email using standardized scripts
• Experience managing complex operational tracking workflows, including monitoring participant status across multiple study pathways
• Advanced knowledge or experience building and maintaining databases using REDCap or similar data capture systems
• Familiarity with clinical research management systems such as OnCore, eREG, Epic/EMR, or other EDC platforms