Clinical Lab Process Development Associate I- Cell Factory

Job Responsibilities

• Maintain and optimize mammalian cell culture systems for screening experiments.
• Apply functional genomics techniques, including epigenomics, single-cell, transcriptomics, and CRISPR-based assays in human cells and tissues.
• Follow standard operating procedures.
• Perform only those high complexity tests that are authorized by the Laboratory Director and require a degree of skill commensurate with the individual’s education, training, experience, and technical abilities.
• Adhere to the laboratory’s quality control policies, document all quality control activities, instrument and procedural calibrations and maintenance performed.
• Follow the laboratory's established policies and procedures whenever test systems are not within the laboratory’s established acceptable levels of performance.
• Be capable of identifying problems that may adversely affect test performance or reporting of test results. Correct the problems according to procedures or immediately notify the General Supervisor, Technical Supervisor, Clinical Consultant or Laboratory Director.
• Document all corrective actions taken when test systems deviate from the laboratory's established performance specifications.
• Review and monitor quality metrics and communicate results to others in the Platform during dedicated meetings as needed.

Minimum Requirements

• BS/BA degree in Biology or Chemistry.
• 1+ years of relevant full time laboratory experience in this specialty subsequent to obtaining B.S./B.A. degree is required.
• Solid knowledge of basic aseptic / mammalian cell culture laboratory techniques required as a part of the above 1 year of experience.
• Strong analytical skills, problem solving ability, and innovation aptitude required.
• Recent (within the last year) laboratory experience with the use of standard cell lab equipment such as pipettes, centrifuges, biosafety cabinets, microscopes, gel electrophoresis required.
• Knowledge of high-throughput screening and automation and/or experience working in a high throughput production setting is desired, but not required.
• Experience with genome editing tools including CRISPR targeting in various human cell types is preferred.
• Strong hands-on experience in molecular biology, genomics, and cellular biology (cell-based assays) is preferred.
• Familiarity with single cell sequencing methods preferred.
• Experience with iPSCs, cell line and/or primary cell culture preferred.