Clinical Engagement Lead - West / Midwest

About the role

The Clinical Engagement Lead, US is a field-based role responsible for building and managing investigator and site relationships across the globe in support of Beeline Medicines' clinical trial portfolio. This role serves as the primary site-facing liaison between the organization and its global clinical investigators, academic medical centers, and research sites.

Responsibilities

• Build and manage a portfolio of region/country investigator and clinical site relationships in the I&I therapeutic area — identifying, engaging, and developing long-term partnerships with principal investigators, academic medical centers, community research sites, and subspecialty practices relevant to Beeline's clinical programs.
• Lead site identification and feasibility activities for clinical trials — conducting operational site assessments, evaluating investigator interest and patient population access, and providing strategic recommendations to Clinical Development and Clinical Operations on site selection and activation.
• Serve as the primary clinical liaison to regional/country level investigators — facilitating peer-to-peer scientific exchange on Beeline's pipeline, conducting protocol discussions, supporting site initiation and training, and maintaining ongoing engagement with investigators throughout the trial lifecycle.
• Support clinical trial enrollment and retention at region/country sites — working proactively with investigators and site staff to identify enrollment challenges, implement site-level solutions, and maintain site motivation and engagement across all active Beeline studies.
• Capture and communicate region/country clinical landscape intelligence — including investigator perspectives, competitive trial activity, site capacity trends, and unmet medical need insights — back to Clinical Development, Medical Affairs, and Commercial teams in a structured, actionable manner.
• Partner with Medical Affairs MSLs to ensure coordination and alignment of scientific engagement activities at the investigator level — establishing clear boundaries between clinical trial support and medical affairs activities and collaborating to maximize the impact of both.
• Represent organization clinical and scientific meetings, investigator symposia, disease-area conferences, and site visits — engaging with the clinical research community as a credible, knowledgeable, and trusted organizational representative.
• Develop and implement site engagement strategies to improve study start-up, enrollment performance, retention, and site satisfaction.
• Partner closely with investigators, study coordinators, and site staff to support patient identification and recruitment efforts.
• Provide operational guidance and best practices to sites related to diverse patient enrollment and community engagement.
• Conduct regular field engagement with investigative sites and community stakeholders to strengthen study execution and recruitment performance.
• Monitor enrollment trends, site performance metrics, and patient engagement effectiveness using data-driven approaches.
• Identify enrollment risks proactively and implement mitigation and recovery plans.

Qualifications

• Education: Bachelors degree in scientific or related discipline required. Advanced degree preferred—MS or MPH in a relevant clinical, biomedical, or pharmaceutical sciences discipline.
• Experience: 8+ years of experience in clinical development, clinical research, clinical operations, or a field-based clinical engagement role within the pharmaceutical or biotech industry.
• Experience: Demonstrated experience managing investigator relationships and supporting clinical trial site activation and enrollment.
• Therapeutic Area: Experience in immunology, inflammation, or a related therapeutic area strongly preferred.
• Collaboration: Experience collaborating with CROs, investigative sites, and field medical teams, including MSL partnerships.
• Knowledge: Strong scientific and clinical knowledge of immunology and inflammation — including disease biology, standard of care, clinical trial design considerations, and the competitive clinical research landscape across relevant I&I indications.
• Site Management: Expertise in clinical trial site management and investigator engagement — including site feasibility assessment, investigator identification and qualification, site initiation support, and enrollment optimization strategies.
• Regulations: Working knowledge of GCP requirements, ICH guidelines, and FDA regulations governing investigator interactions, clinical site oversight, and field-based clinical development activities.
• Leadership: Highly self-directed field professional — manages a complex investigator portfolio independently, prioritizes site engagement activities strategically, and operates with minimal supervision across a broad geography.
• Relationship Building: Relationship-driven and trusted clinical trial resource — builds genuine, long-term partnerships with investigators and site staff based on scientific credibility, reliability, and authentic commitment to supporting research excellence.
• Field Intelligence: Proactive field intelligence contributor — consistently translates field observations into actionable insights that improve program strategy, site selection, and enrollment performance.