Chemist II - Bioconjugation

Duties And Responsibilities

• Aid in the conjugation of proteins with various payloads, including but not limited to oligonucleotides, small molecule dyes, and others.
• Perform purification of proteins and conjugates using established techniques on FPLC systems.
• Conduct analytical assays to characterize proteins and conjugates, including but not limited to LCMS, SEC, IEX, and others.
• Maintain accurate and detailed records of experiments, procedures, and results using ELNS.
• Ensure all documentation is compliant with company standards and regulatory requirements.
• Contribute to the maintenance of the laboratory.
• Collaborate with senior chemists and other team members to support ongoing projects.
• Use general laboratory equipment including pipettors, centrifuges, incubators, biological safety cabinets, and balances.
• Work with software for capturing and analyzing data, including instrument-specific software, Microsoft Office, LIMS, electronic laboratory notebooks, and others.
• Identify, troubleshoot, and suggest technical solutions to clients and management.
• Follow guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.
• Comply with clients' and Company management systems in accordance with appropriate regulatory agencies.
• Perform other duties as defined by the Manager, department needs, and workload.

Requirements

• Hands-on experience in protein purification and/or bioconjugation is a plus.
• Strong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish MX, Water’s QDA, as well as basic laboratory techniques and equipment (pipetting, mass spectrometry, chromatography).
• Basic understanding of biochemistry, bioconjugation, and stoichiometry.
• Strong organizational skills and time management skills.
• Effective communication skills for collaborating with team members and conveying technical information clearly.
• Strong problem-solving abilities and critical thinking skills.
• Ability to organize and prioritize workload to meet or exceed deadlines.
• Individual and Team work ethic.
• Proficiency with Windows, Word & Excel.
• Strong attention to detail and ability to follow protocols precisely.
• Positive attitude, self-motivated, high level of engagement.
• Eagerness to learn and adapt in a fast-paced environment.
• Champions and adheres to company values including team engagement.

Qualifications

• Education: A Bachelor's Degree in Chemistry, Chemical/Biomedical engineering, pharmaceutical sciences or a related field with 1-2 years of experience, or a Master’s degree with 0-1 year of experience.