CHEMIST II

Chemist II Location: Indianapolis, Indiana, US Type of contract: Permanent Posting date: Sep 11, 2026 Job offer reference: 214137 Overview: Business Title: Chemist II – RNA Synthesis Position Title: Analyst II Division: Consumer Products Services Entity: Consumer Products Services/ATL Location: Indianapolis, IN Reports to: Manager FLSA: Non-exempt Hours Worked: Typically, Monday through Friday, forty-hours per week. However, must be flexible to meet the needs of the department and complete other projects as assigned. Position Summary: The Chemist II is responsible for assisting with synthesis and downstream processing of oligo synthesis using various analytical techniques. AKTA, LC-MS, UPLC, LTQ, QDA analytical instruments are used. This person will assist with training new staff, work on multiple projects simultaneously and stay current with new modifications of oligonucleotides. Duties And Responsibilities: It is everyone’s responsibility to live out our Values and Absolutes by Shaping a World of Trust while ensuring responsible progress. Independently perform downstream processing of oligo synthesis: cleavage, deprotection, purification, desalting and annealingBioconjugation of single strand oligonucleotideUse of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balancesInstrumentation for methods and techniques described include various synthesizers, LC-MS, UPLC, LTQ, QDA, Nanodrop, etc.Familiarity with various statistical analysis tools and able to solve technical problems and make recommendations for improvementWork closely with members of the RNAi scale up chemistry team to understand and validate requirements for synthesis scaleup and downstream processingReview literature to stay current on new methods for oligonucleotides and provide technical solutions to clients and managementLab experience with solution preparation, separation, quantification, synthesis methodologies for DNA/RNA, proteins, oligonucleotides, etc.Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.Detailed record keeping of daily experiments in ELNsGeneral Lab MaintenanceTrain new staff membersIdentify, troubleshoot, and suggest technical solutions to clients and managementFollow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.Perform other essential tasks projects and responsibilities as required.Other duties as defined by the Manager, department needs and workload Skills & Proficiencies: Experience, troubleshooting, and optimizing synthetic protocols on various synthesizersStrong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water’s QDA, etc.Experience in developing new chromatographic methods (IEX/RP-HPLC, SPE, LC-MS).Strong organizational skills and ability to prepare written technical reportsStrong oral communication skills in presenting facts and recommendationsConfident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environmentWritten and verbal communication skills including the ability to communicate effectively in a group setting, with colleagues and clientsAbility to perform multiple tasksAbility to organize and prioritize workload to meet or exceed deadlinesIndividual and Team work ethicProficiency with Windows, Word & ExcelAttention to detailPositive attitude, self-motivated, high level of engagementChampions and adheres to company values including team engagement Education And Experience: Degree requirement: Bachelor's Degree in Chemistry, Biochemistry, or closely related fieldMinimum of one (1) year of experience with oligonucleotide chemistry An equivalent combination of education and experience may be accepted in lieu of above Compensation Range: $28.00-$31.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset). READY TO LEAVE YOUR MARK IN A SMARTER SOCIETY? Duties And Responsibilities: It is everyone’s responsibility to live out our Values and Absolutes by Shaping a World of Trust while ensuring responsible progress. Independently perform downstream processing of oligo synthesis: cleavage, deprotection, purification, desalting and annealingBioconjugation of single strand oligonucleotideUse of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balancesInstrumentation for methods and techniques described include various synthesizers, LC-MS, UPLC, LTQ, QDA, Nanodrop, etc.Familiarity with various statistical analysis tools and able to solve technical problems and make recommendations for improvementWork closely with members of the RNAi scale up chemistry team to understand and validate requirements for synthesis scaleup and downstream processingReview literature to stay current on new methods for oligonucleotides and provide technical solutions to clients and managementLab experience with solution preparation, separation, quantification, synthesis methodologies for DNA/RNA, proteins, oligonucleotides, etc.Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.Detailed record keeping of daily experiments in ELNsGeneral Lab MaintenanceTrain new staff membersIdentify, troubleshoot, and suggest technical solutions to clients and managementFollow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.Perform other essential tasks projects and responsibilities as required.Other duties as defined by the Manager, department needs and workload Skills & Proficiencies: Experience, troubleshooting, and optimizing synthetic protocols on various synthesizersStrong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water’s QDA, etc.Experience in developing new chromatographic methods (IEX/RP-HPLC, SPE, LC-MS).Strong organizational skills and ability to prepare written technical reportsStrong oral communication skills in presenting facts and recommendationsConfident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environmentWritten and verbal communication skills including the ability to communicate effectively in a group setting, with colleagues and clientsAbility to perform multiple tasksAbility to organize and prioritize workload to meet or exceed deadlinesIndividual and Team work ethicProficiency with Windows, Word & ExcelAttention to detailPositive attitude, self-motivated, high level of engagementChampions and adheres to company values including team engagement Education And Experience: Degree requirement: Bachelor's Degree in Chemistry, Biochemistry, or closely related fieldMinimum of one (1) year of experience with oligonucleotide chemistry An equivalent combination of education and experience may be accepted in lieu of above Compensation Range: $28.00-$31.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset). Duties And Responsibilities: It is everyone’s responsibility to live out our Values and Absolutes by Shaping a World of Trust while ensuring responsible progress. Independently perform downstream processing of oligo synthesis: cleavage, deprotection, purification, desalting and annealingBioconjugation of single strand oligonucleotideUse of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balancesInstrumentation for methods and techniques described include various synthesizers, LC-MS, UPLC, LTQ, QDA, Nanodrop, etc.Familiarity with various statistical analysis tools and able to solve technical problems and make recommendations for improvementWork closely with members of the RNAi scale up chemistry team to understand and validate requirements for synthesis scaleup and downstream processingReview literature to stay current on new methods for oligonucleotides and provide technical solutions to clients and managementLab experience with solution preparation, separation, quantification, synthesis methodologies for DNA/RNA, proteins, oligonucleotides, etc.Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.Detailed record keeping of daily experiments in ELNsGeneral Lab MaintenanceTrain new staff membersIdentify, troubleshoot, and suggest technical solutions to clients and managementFollow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.Perform other essential tasks projects and responsibilities as required.Other duties as defined by the Manager, department needs and workload Skills & Proficiencies: Experience, troubleshooting, and optimizing synthetic protocols on various synthesizersStrong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water’s QDA, etc.Experience in developing new chromatographic methods (IEX/RP-HPLC, SPE, LC-MS).Strong organizational skills and ability to prepare written technical reportsStrong oral communication skills in presenting facts and recommendationsConfident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environmentWritten and verbal communication skills including the ability to communicate effectively in a group setting, with colleagues and clientsAbility to perform multiple tasksAbility to organize and prioritize workload to meet or exceed deadlinesIndividual and Team work ethicProficiency with Windows, Word & ExcelAttention to detailPositive attitude, self-motivated, high level of engagementChampions and adheres to company values including team engagement Education And Experience: Degree requirement: Bachelor's Degree in Chemistry, Biochemistry, or closely related fieldMinimum of one (1) year of experience with oligonucleotide chemistry An equivalent combination of education and experience may be accepted in lieu of above Compensation Range: $28.00-$31.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset).