Cellular Biologist II, Global Stem Cell Array

About the role

The Cellular Biologist II, Global Stem Cell Array, performs project planning, experimental design, method development, execution of laboratory procedures, adaptation of protocols, data collection and analysis, documentation, and contribution to reports and other written materials for human/mammalian cell culture.

This role involves regular collaboration with cross-functional partners such as project managers, engineering teams, and software or technical support personnel to ensure smooth day-to-day laboratory operations in a production-focused environment.

Responsibilities

• Implement and perform cell biology-related tasks and procedures.
• Plan and monitor resources needed for cell culture (manual or automated), spatial transcriptomics, and hyperplexed imaging technologies.
• Maintain inventory control and coordinate space, equipment, and facilities.
• Document results, implement protocols from literature, troubleshoot issues, and analyze variations in testing protocols.
• Modify, refine, or adapt techniques, procedures, and quality control measures.
• Lead the exchange of research information through demonstration and instruction.
• Perform and monitor automated and manual cell culture and related activities, adapting protocols and developing new workflows.
• Execute workflows including fibroblast expansion, reprogramming, iPSC expansion on robotic platforms, and manual processes as required.
• Store and withdraw specimens from liquid nitrogen and freezers, and prepare media and reagents.
• Work closely with the laboratory operations team to ensure accurate and efficient reagent/consumable inventory.
• Plan and monitor resources for the Global Stem Cell Array.
• Collaborate with departmental leadership and a multidisciplinary team of scientists and technical specialists.
• Provide documentation and feedback, including creating and modifying SOPs, filing tickets to software and automation teams, and participating in inter- and intra-team meetings.
• Collaborate with engineers and other staff to resolve complex issues.

Requirements

Bachelor’s degree or foreign equivalent in biology, biotechnology, forensic science, or a related field, and two years of experience in a professional laboratory scientific role performing both automated and manual cell culture operations for induced pluripotent stem cell (iPSC) lines in compliance with Laboratory Information Management Systems.

Skills

All qualified applicants must have experience with the following proficiencies over a period of 24 months:

• Automated iPSC derivation and cell culture operations, including production and handling of biological materials to support automated iPSC reprogramming, expansion, maintenance, and assay execution (e.g., robotic media exchange, passaging, thawing, and cryopreservation).
• Processing whole blood, skin, saliva, and fibroblast samples; isolation of PBMCs using manual and automated array systems; preparation of biological inputs for downstream reprogramming and discovery workflows within Laboratory Information Management Systems platforms.
• Executing fibroblast reprogramming protocols, initiating stem cell discovery pipelines, and transitioning primary cell types into pluripotent states under controlled manual and automated conditions.
• Implementation, development, and continuous improvement of novel automated assays and workflows; analysis and assessment of robotic system performance; identification and resolution of automation-related process issues.
• Maintenance of organized, accurate records; independent troubleshooting with concise error reporting to scientific teams; exclusive use of Laboratory Information Management Systems for sample and process traceability.

Pay

Between $73,382 and $82,311 per year.

About the employer

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees across the United States (Maine, Connecticut, California), Japan, and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in improving human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease.