Cardiometabolic / Endocrinology Principal Investigator

About the role

Tekton Research is seeking a physician with expertise in cardiometabolic and endocrinology clinical research to serve as Principal Investigator in Austin, Texas. The role will lead clinical trials for conditions such as diabetes, obesity, metabolic disease, lipid disorders, and cardiovascular risk reduction, providing scientific and clinical leadership including compliance, patient safety, and oversight. The ideal candidate will drive scientific leadership in these areas while supporting strategic site growth and sponsor partnerships.

Responsibilities

• Serve as Principal Investigator for cardiometabolic and endocrinology clinical trials (e.g., diabetes, obesity, metabolic disease, lipid disorders, cardiovascular risk reduction).
• Provide medical and scientific leadership for study execution, patient safety, and protocol compliance.
• Partner with sponsors and CROs on feasibility, protocol development, and study design feedback.
• Support expansion of Tekton’s cardiometabolic and endocrine research portfolio.
• Participate in sponsor meetings, site selection visits, and industry engagements.
• Contribute to patient recruitment strategy and enrollment optimization.
• Present clinical insights and represent Tekton at industry and scientific meetings.
• Collaborate cross‑functionally with operations, recruitment, and business development teams.
• Ensure compliance with FDA regulations, ICH‑GCP standards, and study protocols.

Qualifications

• MD or DO with an active medical license.
• Board certification or specialization in Endocrinology, Internal Medicine, or a related specialty.
• Experience in cardiometabolic or endocrine patient care (diabetes, obesity, metabolic syndrome, lipid disorders, etc.).
• Clinical research experience as a Principal Investigator or Sub‑Investigator preferred.
• Experience interacting with pharmaceutical sponsors or CROs preferred.
• Strong interest in advancing cardiometabolic innovation and therapeutic development.
• Ability to work collaboratively across clinical and operational teams.
• Ability to travel (15‑20%).

Skills

• Prior leadership in cardiometabolic or endocrine clinical trials.
• Experience in obesity, diabetes, NASH/MASH, lipid management, or cardiovascular outcomes studies.
• Publications, speaking engagements, or scientific leadership experience.
• Established relationships within industry or academic networks.
• Experience supporting site growth or therapeutic program development.

Pay

Competitive physician salary plus productivity‑based incentives.

Schedule

Full‑time, on‑site, exempt position with approximately 15‑20% travel.