Biological Structures Data Engineer I/II

Job Summary

Iambic Therapeutics is seeking a Biological Structures Data Engineer to join the NeuralPLexer team and own the data pipelines for acquiring, curating, and transforming experimental and synthetic data to train the next generation of NeuralPLexer models.

Key Responsibilities

• Understand, maintain, and enhance existing data pipelines, including parsing and validation of structural data (.cif/PDB and beyond)
• Integrate and adapt data from a range of public and proprietary sources into reliable, reusable pipelines
• Work closely with ML scientists to ensure their data needs are met
• Ensure all data is stored in a secure, robust, and retrievable manner
• Perform code reviews and exemplify software engineering best practices. Communicate technical work effectively across a cross-functional research and engineering team

Qualifications

• Engineer I: PhD or equivalent experience in Bioinformatics, Computational Biology, Cheminformatics or a related field
• Engineer II: PhD or equivalent experience in Bioinformatics, Computational Biology, Cheminformatics or a related field with 3+ years of relevant experience
• Hands-on familiarity with structural biology data — .cif files, the PDB, and the practical challenges of working with real-world molecular structures
• Strong software engineering practices, with a focus on maintainable, well-tested systems
• Proficiency in Python
• Comfortable operating in a research-driven environment; developing, learning, and adapting cutting edge technologies
• Strong collaboration skills and the ability to communicate across a cross-functional research and engineering team

PREFERRED EXPERIENCE

• Designing data pipelines or data infrastructure for heterogeneous or large-scale datasets
• Familiarity with additional drug-discovery-relevant data types
• Experience contributing to a data lake or comparable centralized data platform
• Familiarity with auxiliary data or data transformations relevant to protein structure prediction
• Exposure to cloud-based systems (e.g., AWS, Kubernetes) and/or HPC

About Iambic Therapeutics

Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need.

MISSION & CORE VALUES

The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

Career Opportunities

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

Compensation Range

$129.6K - $190K