Bioinformatics Research Analyst - Pediatrics Newborn Medicine

About the Role

This Bioinformatics Research Analyst is a dry-lab position and will play a key role in a collaborative team dedicated to uncovering the genomic basis of rare diseases as part of the Washington University Undiagnosed Diseases Network and other WashU local rare disease projects. This role focuses on working with large genomic datasets to analyze data from whole genome and exome sequencing, short- and long-read RNA sequencing, long-read genome sequencing, and epigenomics data. This technician will support the design, implementation, and execution of bioinformatics workflows and pipelines to facilitate variant discovery, perform variant analysis/prioritization based on biological relevance, manage storage and transfer of large datasets, and assist in evaluating new computational methods and tools.

Responsibilities

• Implements, manages, and runs computational bioinformatics pipelines on a local high-performance computing cluster to analyze genomic datasets.
• Maintain and manage large datasets, including data storage and data transfer of genomic data.
• Contribute to developing and refining computational workflows to improve the efficiency and accuracy of genomic data processing and analysis.
• Conduct variant analysis and curation, helping to identify genomic variants underlying rare disease.
• Work closely with a multidisciplinary team to communicate findings and interpret results within the context of rare disease research.
• Assist in preparing project reports, presentations, and manuscripts as needed.
• Performs other duties as assigned.

Qualifications

• Bachelor's degree or combination of education and/or experience may substitute for minimum education.
• Relevant experience (2 years).

Preferred Qualifications

• Master's degree in Bioinformatics or related field.
• Skills: Analytical Thinking, Bioinformatics Tools, Communication, Complex Data Analysis, Computational Biology, Critical Reasoning, Exome Sequencing, Gene Expression Microarray, Genome Sequencing, Genomic Data Analysis, Group Problem Solving, Human Genetics, Model Organism, Nextflow, RNA-Seq, Workflow Management Systems.

Benefits

• Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copays/coinsurance.
• Free Metro transit U-Pass for eligible employees.
• Defined contribution (403(b)) Retirement Savings Plan with university contributions starting at 7%.
• Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more.
• 4 weeks of caregiver leave to bond with your new child.
• Family care resources for childcare and adult care.
• Tuition coverage up to 100% at WashU and 40% elsewhere for dependent undergraduate-level college tuition after seven years.