Bioinformatics Analyst I - Lung Regeneration Research

The Hu Lab is focused on uncovering therapeutic pathways to promote small airway and alveolar regeneration, particularly in diseases where current treatments are limited, such as COPD and BPD. The lab employs cutting-edge methodologies, including single-cell and spatial transcriptomics, patient-derived lung organoids, ex vivo precision-cut lung slices, and transgenic animal disease models to advance understanding of lung epithelial progenitor cell function and develop innovative strategies for lung tissue repair.

About the role

We are seeking a Bioinformatics Analyst with strong expertise in spatial transcriptomics, scRNA-seq, and Visium HD to analyze single-cell and spatial data, support lab training, and advance lung regeneration research.

Responsibilities

• Analyze and interpret genomic data to identify potential disease-causing mutations or genetic variations.
• Develop and implement bioinformatics pipelines and workflows for genomic data analysis.
• Collaborate with research teams to design experiments and analyze data.
• Maintain and update genomic databases and software tools.
• Communicate findings and results to stakeholders in a clear and concise manner.
• Stay up-to-date with the latest developments in bioinformatics and genomics research.

Requirements

• Bachelor’s degree in biology, molecular genetics, computer science, bioinformatics, or related field (required).
• M.S. degree in Bioinformatics, Computational Biology, Biostatistics, or a related discipline (preferred).
• Experience in a Linux/Unix environment and familiarity with scripting and process automation (Python/Perl, shell) (preferred).

Skills

• Superior attention to detail and adherence to quality standards.
• Interest in genomics and bioinformatics, with willingness to learn concepts and terminology.
• Excellent verbal and written communication skills.
• Ability to manage multiple projects in a fast-paced environment with changing priorities.
• Ability to effectively collaborate in a dynamic, cross-functional matrix environment.

Physical Requirements

• Occasionally: Standing, Walking
• Frequently: Lifting / Carrying: 0-10 lbs, Lifting / Carrying: 11-20 lbs
• Continuously: Audible speech, Color vision, Computer skills, Decision Making, Depth perception, Hand use: grasping, gripping, turning, Hearing acuity, Interpreting Data, Peripheral vision, Problem solving, Repetitive hand/arm use, Seeing – Far/near, Sitting