Bioinformatician A

About the role

The Kaestner Lab (Dept. of Genetics, University of Pennsylvania) is seeking a meticulous and technically skilled Bioinformatician.

Responsibilities

• Data Organization: Design, implement, and maintain structured file systems, standardized naming conventions, and metadata schemas for bioinformatics data (e.g., NGS, imaging).
• Access & Security: Manage access permissions, version control, and audit trails across HPC, local servers, tape, and cloud platforms.
• Cloud & Archival Storage: Administer tape- and cloud-based storage environments (AWS S3, Dropbox, Box, institutional repositories) and coordinate archival and retrieval strategies.
• Cost Monitoring & Optimization: Track and analyze storage utilization and expenses across on-premises, tape, and cloud systems; develop policies to optimize resource allocation and reduce costs.
• Data Integrity & Backup: Ensure redundancy, perform integrity checks, and manage automated backup processes.
• Data Transfers: Perform secure data transfers to and from public repositories (such as dbGaP, SRA) following institutional and funding agency’s mandated policies.
• Documentation & Training: Maintain comprehensive documentation of file structures, workflows, and storage protocols; train researchers on best practices for data management and archival.
• Preprocessing Pipelines: Execute predefined preprocessing or quality control pipelines (e.g., FASTQ QC, format conversion, alignment) on high-throughput datasets using HPC or cloud workflows.
• Other duties and responsibilities as assigned.

Qualifications

• Bachelor of Science and 3 to 4 years of experience or equivalent combination of education and experience is required.

Benefits

• Health, Life, and Flexible Spending Accounts
• Tuition
• Retirement
• Time Away from Work
• Long-Term Care Insurance
• Wellness and Work-life Resources
• University Resources
• Discounts and Special Services
• Flexible Work Hours
• Penn Home Ownership Services
• Adoption Assistance