Bioassay Scientist - Flow Cytometry

About the role

This position supports an Analytical Development client team responsible for ensuring the consistency, safety, and efficacy of biologics, including cutting-edge cell and gene therapies. The role involves close partnership with bioprocessing, formulation, and data science groups to support manufacturing and quality control activities across the client’s development pipeline. The focus is on developing and executing bioanalytical assays for process development, in-process testing, and lot release within the iPSC induced islet cell therapy program in the Analytical Development Bioassay Team.

Responsibilities

• Design and execute bioanalytical assays including flow cytometry, cell counting, dPCR/qPCR, ELISA, and cell-based bioassays.
• Perform routine sample testing for in-process testing and lot release.
• Optimize assay parameters (specificity, sensitivity, precision, accuracy, linearity, etc.).
• Support assay qualification and lifecycle management.
• Document experiments and protocols using electronic lab notebooks (e.g., Benchling).
• Troubleshoot assay and instrument issues.
• Collaborate cross-functionally with Process Development, R&D, and Quality teams.
• Author technical documentation: protocols, test methods, reports, SOPs.

Requirements

• BS in Biology or related field with at least 3 years of experience in drug development labs OR M.S. in Biology or related field with at least 1 year of experience in drug development labs.
• Hands-on experience with bioanalytical methods including flow cytometry (multi-color flow cytometry with a minimum of 4-6 colors is preferred).
• Proficiency in mammalian cell culture techniques.
• Ability to troubleshoot and interpret experimental results and effectively present conclusions.

Qualifications

• Hands-on experience with dPCR/qPCR and cell-based bioassays, such as glucose-stimulated insulin release, ELISA, and live cell plate assays.
• Experience improving assay throughput by utilizing multi-color flow cytometry and incorporating automated liquid handlers (e.g., Hamilton) and plate-based sample preparations.
• Experience with iPSC differentiation and handling iPSC-derived cells.
• Proficiency in method development and method qualification.
• Proficiency with data analysis tools (e.g., GraphPad Prism, FlowJo) and digital platforms (e.g., Benchling, SharePoint, Veeva).
• Strong troubleshooting and continuous improvement mindset.
• Knowledge of regulatory standards and ICH guidelines.
• Strong time management and organizational skills, with the ability to handle multiple priorities under tight deadlines.
• Excellent communication skills and the ability to work independently and collaborate in a team-oriented, matrixed environment.
• Willingness to take on additional responsibilities as needed, including occasional weekend work.

Benefits

• Comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Eligibility for yearly goal-based bonus & merit-based increases

Pay

$35.00–$41.00 per hour based on education and related experience.

Schedule

Full Time, Monday–Friday, 8:00 am–5:00 pm.