Associate Scientist I
Planet Pharma · Irvine, CA · 1 wk ago
AnalystContract
Target PR Range: 24-34/hr DOE Position Summary We are seeking a detail-oriented and experienced histotechnician for an 8-month contract position supporting routine histology and immunohistochemistry (IHC) operations within the histology laboratory for Skincare R&D and Clinical Development. This is a hands-on, lab-based role responsible for the processing, sectioning, and staining of formalin-fixed paraffin-embedded (FFPE) tissues, as well as performing special stains, IHC assays, and associated imaging/documentation. The ideal candidate is comfortable working independently in a fast-paced environment, maintains rigorous attention to quality and consistency, and has solid foundational histology bench skills. Key Responsibilities Perform routine processing of FFPE tissue specimens, including trimming, embedding, and block preparationSection FFPE tissue blocks using a microtome to produce high-quality, consistent slides for downstream analysisPerform routine histology staining (e.g., H&E) and special stains (e.g., Fontana-Masson, Resorcin Fuchsin, Herovici, etc.) per established SOPsPerform manual and/or automated immunohistochemistry (IHC) staining, including antigen retrieval, antibody optimization support, and chromogenic/fluorescent detectionOperate and maintain histology laboratory equipment (microtomes, tissue processors, embedding stations, autostainers, coverslippers)Perform slide imaging/scanning and organize digital image files for study team reviewMaintain accurate, detailed records of samples, staining runs, and quality control checks in line with lab documentation practicesTroubleshoot staining and tissue quality issues, escalating as appropriateEnsure proper labeling, tracking, and chain-of-custody for tissue specimens and slidesMaintain lab supplies, reagents, and equipment calibration/maintenance logsAdhere to all laboratory safety protocols, including handling of chemicals (formalin, xylene, etc.) and biohazardous materialsSupport general lab organization, inventory management, and cleanliness standardsCollaborate with scientists and lab management within Skincare R&D and Clinical Development to meet study timelines and quality expectations Required Qualifications Associate's or Bachelor's degree in a relevant scientific field (e.g., Biology, Medical Laboratory Science, Histotechnology)Minimum of 1–3 years of hands-on experience in a histology laboratory, including FFPE tissue processing, microtome sectioning, and routine/special stainingStrong attention to detail and consistency in a high-throughput lab environmentAbility to work independently with minimal supervision while following established SOPsGood documentation and record-keeping habitsAbility to safely handle laboratory chemicals and biological specimens Preferred Qualifications HT or HTL certification (ASCP) or eligibilityDemonstrated experience performing IHC staining (manual and/or automated platforms)Familiarity with slide imaging/digital scanning workflowsExperience with automated IHC/special stain platforms (e.g., Leica Bond, Ventana/Roche Discovery, Dako Autostainer)Experience with whole-slide imaging/scanning systemsPrior experience in a pharmaceutical, biotech, or CRO research lab setting (as opposed to clinical diagnostics)Familiarity with GLP or GxP laboratory documentation practicesExperience in skincare/dermatology-focused research or clinical development studies is a plus Work Schedule & Environment On-site, full-time lab-based role (standard business hours, may vary by lab needs)Requires standing/sitting at a lab bench for extended periods and handling laboratory chemicals and biological tissue specimensPersonal protective equipment (PPE) required per lab safety protocols