Associate Scientist

Key Responsibilities

• Design, execute, and manage in vivo pharmacology studies and downstream biochemical and molecular assays to evaluate the efficacy of small-molecule therapeutics for cardiac indications.
• Lead day-to-day oversight of animal study cohorts, including scheduling, dosing, monitoring, and coordination with vivarium staff, ensuring full compliance with IACUC and institutional guidelines.
• Quantify and interpret biomarkers of disease progression and target engagement, integrating functional and molecular endpoints to assess compound performance.
• Collaborate closely with discovery, DMPK, and translational teams to advance compounds through preclinical development, contributing to study design, data interpretation, and go/no-go decisions.
• Maintain rigorous documentation of experimental methods and results; manage datasets; prepare clear, concise data summaries and presentations for internal project team meetings and program reviews.

Qualifications

• BS in Biology, Physiology, Pharmacology, or a related discipline with 8+ years of hands-on research experience or MS with 6+ years of experience.
• Prior experience in a pharmaceutical or biotechnology setting is strongly preferred.
• Demonstrated proficiency in rodent handling and dosing (mouse and rat), including multiple routes of administration is required.
• Experience with cardiac functional assessments (e.g., echocardiography, tail-cuff blood pressure measurements, or related techniques) is highly desirable.
• Extensive hands-on experience in biochemical and molecular biology assays, such as Western blotting, qPCR, immunohistochemistry, and enzyme-based assays.
• Experience with handling mammalian cell culture or primary cardiomyocytes is a plus.
• Ability to analyze, interpret, and clearly communicate complex datasets, both in written reports and oral presentations.

Pay Range

In the U.S., the hiring pay range for fully qualified candidates is $121,500-$141,750 per year. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.

About the Role

We are seeking a highly motivated Associate Scientist to support pharmacology efforts across muscle biology programs. The ideal candidate is a proactive and collaborative scientist who thrives in a multidisciplinary environment and contributes meaningfully to the progression of compounds through preclinical research and development.

Benefits

We are an equal opportunity employer and celebrate diversity at our company. We are committed to creating a work environment where everyone feels valued and respected. We strive to foster an inclusive culture that encourages collaboration, innovation, and continuous learning.

Schedule

We offer flexible working arrangements to accommodate the diverse needs of our employees. Our goal is to provide a supportive and productive work environment that allows you to thrive both personally and professionally.